STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cry1Cryptochrome-1; Blue light-dependent regulator that is the input of the circadian feedback loop. Has no photolyase activity for cyclobutane pyrimidine dimers or 6-4 photoproducts. Regulation of expression by light suggests a role in photoreception for locomotor activity rhythms. Functions, together with per, as a transcriptional repressor required for the oscillation of peripheral circadian clocks and for the correct specification of clock cells. Genes directly activated by the transcription factors Clock (Clk) and cycle (cyc) are repressed by cry (By similarity); Belongs to the DNA ph [...] (545 aa)    
Predicted Functional Partners:
A7UUK1_ANOGA
AGAP008288-PA.
    
 0.914
Q7Q6R8_ANOGA
AGAP005711-PA.
    
 0.892
Q7QNA5_ANOGA
AGAP012873-PA.
   
 0.887
Q7Q3B8_ANOGA
AGAP007801-PA.
   
  
 0.817
Q7PYB3_ANOGA
AGAP001856-PA.
   
 0.804
A0NES1_ANOGA
PAR-domain protein 1.
   
  
 0.792
Q7QGF4_ANOGA
AGAP009335-PA.
    
 0.760
A7UV10_ANOGA
AGAP010787-PA.
    
 0.758
Q7QC91_ANOGA
Protease m1 zinc metalloprotease.
     
 0.755
F5HLF5_ANOGA
Aminopeptidase N.
     
 0.743
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
Server load: low (28%) [HD]