STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMSA_ANOGAProbable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA (By similarity); Belongs to the aldehyde dehydrogenase family. (521 aa)    
Predicted Functional Partners:
Q7PNN6_ANOGA
3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
   
 0.991
GLYR1_ANOGA
Putative oxidoreductase GLYR1 homolog; May have oxidoreductase activity. Belongs to the HIBADH-related family. NP60 subfamily.
   
 0.963
Q7QIN5_ANOGA
4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
 
 0.956
Q7PYI1_ANOGA
Butyryl-CoA dehydrogenase.
   
 
 0.943
Q7PG41_ANOGA
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
   
 
 0.937
Q7PQI7_ANOGA
Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family.
  
0.935
Q7Q165_ANOGA
AGAP009944-PA; Belongs to the aldehyde dehydrogenase family.
  
0.930
Q7Q8J0_ANOGA
AGAP008602-PA.
   
 
 0.930
Q7QAQ9_ANOGA
Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family.
  
0.929
Q7QIF7_ANOGA
Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.929
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.