STRINGSTRING
OR7_ANOGA protein (Anopheles gambiae) - STRING interaction network
"OR7_ANOGA" - Odorant receptor coreceptor in Anopheles gambiae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OR7_ANOGAOdorant receptor coreceptor; Odorant coreceptor which complexes with conventional odorant receptors (ORs) to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability. Orco is a universal and integral part of the functional odorant receptor, involved in the dendritic localization of other olfactory receptors. Can form functional ion channels in the absence of an odor-binding OR. Plays a key role in preferred attraction of females for humans over non-human hosts for blood feeding. Human attraction plays a crucial role in the transmission of [...] (478 aa)    
Predicted Functional Partners:
1272638
Ionotropic receptor IR8a; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family (828 aa)
     
 
  0.933
AGAP008604-PC
AGAP008604-PA; glycyl-tRNA synthetase (783 aa)
           
  0.893
1279695
Ionotropic receptor IR25a; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family (914 aa)
       
 
  0.891
SCRB1
Sensory neuron membrane protein 1; Plays an olfactory role that is not restricted to pheromone sensitivity (545 aa)
     
   
  0.869
GR22_ANOGA
Gustatory and odorant receptor 22; Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. GPRgr22 and GPRgr24 together are sufficient for olfactory carbon dioxide- chemosensation (467 aa)
           
  0.851
GR24_ANOGA
Gustatory and odorant receptor 24; Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. GPRgr22 and GPRgr24 together are sufficient for olfactory carbon dioxide- chemosensation (457 aa)
           
  0.850
AGAP011968-PA
AGAP011968-PA; Ionotropic receptor IR76b (511 aa)
       
 
  0.847
1275727
Ionotropic receptor IR64a (567 aa)
       
 
  0.836
OBP4
Odorant binding protein antennal (150 aa)
     
   
  0.829
1274253
prolyl-tRNA synthetase (461 aa)
           
  0.767
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae, Anopheles gambiae sensu stricto
Server load: low (16%) [HD]