node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Q7PMI7_ANOGA | Q7Q6F9_ANOGA | Q7PMI7 | Q7Q6F9 | Homogentisate 1,2-dioxygenase. | Fumarylacetoacetase. | 0.991 |
Q7PMI7_ANOGA | Q7QHX1_ANOGA | Q7PMI7 | Q7QHX1 | Homogentisate 1,2-dioxygenase. | AGAP001038-PA. | 0.478 |
Q7PMI7_ANOGA | T23O_ANOGA | Q7PMI7 | O77457 | Homogentisate 1,2-dioxygenase. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.673 |
Q7PMI7_ANOGA | kh | Q7PMI7 | Q7Q6A7 | Homogentisate 1,2-dioxygenase. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.842 |
Q7PS32_ANOGA | Q7Q6H2_ANOGA | Q7PS32 | Q7Q6H2 | AGAP000326-PA. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.885 |
Q7PS32_ANOGA | Q7Q9Z4_ANOGA | Q7PS32 | Q7Q9Z4 | AGAP000326-PA. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.822 |
Q7PS32_ANOGA | Q7QKE7_ANOGA | Q7PS32 | Q7QKE7 | AGAP000326-PA. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.727 |
Q7PS32_ANOGA | kh | Q7PS32 | Q7Q6A7 | AGAP000326-PA. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.879 |
Q7Q6F9_ANOGA | Q7PMI7_ANOGA | Q7Q6F9 | Q7PMI7 | Fumarylacetoacetase. | Homogentisate 1,2-dioxygenase. | 0.991 |
Q7Q6F9_ANOGA | T23O_ANOGA | Q7Q6F9 | O77457 | Fumarylacetoacetase. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.639 |
Q7Q6F9_ANOGA | kh | Q7Q6F9 | Q7Q6A7 | Fumarylacetoacetase. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.836 |
Q7Q6H2_ANOGA | Q7PS32_ANOGA | Q7Q6H2 | Q7PS32 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | AGAP000326-PA. | 0.885 |
Q7Q6H2_ANOGA | Q7Q9Z4_ANOGA | Q7Q6H2 | Q7Q9Z4 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.418 |
Q7Q6H2_ANOGA | Q7QKE7_ANOGA | Q7Q6H2 | Q7QKE7 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.999 |
Q7Q6H2_ANOGA | kh | Q7Q6H2 | Q7Q6A7 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.827 |
Q7Q9Z4_ANOGA | Q7PS32_ANOGA | Q7Q9Z4 | Q7PS32 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | AGAP000326-PA. | 0.822 |
Q7Q9Z4_ANOGA | Q7Q6H2_ANOGA | Q7Q9Z4 | Q7Q6H2 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.418 |
Q7Q9Z4_ANOGA | Q7QKE7_ANOGA | Q7Q9Z4 | Q7QKE7 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.651 |
Q7Q9Z4_ANOGA | kh | Q7Q9Z4 | Q7Q6A7 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. | 0.865 |
Q7QHE7_ANOGA | Q7QKH2_ANOGA | Q7QHE7 | Q7QKH2 | AGAP011158-PA. | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites. | 0.948 |