STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FADDIMD pathway signalling Fas-Associated Death Domain (FADD). (255 aa)    
Predicted Functional Partners:
IMD
IMD pathway signalling Immune Deficiency (Imd).
    
 0.993
CASPL1
AGAP011693-PA; Belongs to the peptidase C14A family.
    
 0.986
IAP2
Inhibitor of apoptosis 2.
   
 0.802
REL2
IMD pathway signalling NF-kappaB Relish-like transcription factor.
    
 0.754
IKK1
AGAP009166-PA.
    
 0.729
Q7PZ29_ANOGA
AGAP011694-PA.
    
 0.694
A7UU92_ANOGA
Transcription factor AP-1.
      
 0.592
Q5TVZ3_ANOGA
AGAP011138-PA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 0.502
Q7QG29_ANOGA
Cyclin G-associated kinase.
    
 0.501
CASPL2
Long caspase (CASPL2); Belongs to the peptidase C14A family.
   
 0.479
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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