STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASPS3Short caspase 3; Belongs to the peptidase C14A family. (292 aa)    
Predicted Functional Partners:
F5HM39_ANOGA
Tyrosine-protein kinase.
    
 0.750
Q7PPB4_ANOGA
Tyrosine-protein kinase.
    
 0.750
Q7Q5D3_ANOGA
Tyrosine-protein kinase.
    
 0.750
Q7QE10_ANOGA
Tyrosine-protein kinase.
    
 0.750
Q7QE59_ANOGA
AGAP000810-PA.
    
 0.733
Mcm6
DNA replication licensing factor Mcm6; Acts as component of the Mcm2-7 complex (Mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the Mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
  
 0.584
TEP10
Thioester-containing protein 10.
      
 0.580
TEP12
AGAP008654-PA.
      
 0.575
Q7PQW0_ANOGA
AGAP002651-PA.
   
 0.561
Q7PWU2_ANOGA
AGAP008851-PA.
    
 0.513
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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