STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q5TQD3_ANOGAAGAP008299-PA. (376 aa)    
Predicted Functional Partners:
Q7Q186_ANOGA
AGAP009921-PA.
   
 0.856
Q7Q886_ANOGA
AGAP008747-PA.
    
 
 0.781
Q7QE09_ANOGA
AGAP010711-PA.
   
 
 0.755
Cbp80
Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. In the CBC complex, Cbp80 does not bind directly capped RNAs (m7GpppG- capped RNA) but is [...]
   
 
 0.702
Q7QD89_ANOGA
Tyrosine--tRNA ligase.
   
  
 0.696
Q7PZJ5_ANOGA
AGAP011944-PA.
   
 
 0.679
Cbp20
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. In the CBC complex, Cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requ [...]
    
 
 0.671
Q7QBT6_ANOGA
Exosome complex exonuclease.
    
 
 0.649
Q7QHS2_ANOGA
Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family.
    
   0.649
Q5TX48_ANOGA
GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.
   
 
 0.625
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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