STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Q7QCA3_ANOGAEukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (634 aa)    
Predicted Functional Partners:
eIF3-S9
Eukaryotic translation initiation factor 3 subunit B; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
   
 
 0.950
Q7Q0B4_ANOGA
AGAP012368-PA.
   
 
 0.637
Q5TVQ5_ANOGA
40S ribosomal protein S19.
    
  0.616
Q7Q2U9_ANOGA
AGAP004824-PA.
   
  
 0.611
Q7PQ65_ANOGA
5'-3' exoribonuclease 1.
    
 
 0.608
RpS13
40S ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family.
   
  0.604
Q7PUC9_ANOGA
40S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
   
  0.583
Q7QC42_ANOGA
40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family.
    
  0.583
Q7PJE1_ANOGA
40S ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family.
   
  0.579
Q7PT95_ANOGA
40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family.
 
  
  0.579
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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