STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alpha-AdaptinAP-2 complex subunit alpha; Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Alpha adaptin is a subunit of the plasma membrane adapter (By similarity). (934 aa)    
Predicted Functional Partners:
Q7PY17_ANOGA
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
 0.999
Q7QIY5_ANOGA
AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.
   
 0.999
Q7PX81_ANOGA
AP complex subunit beta.
   
0.996
Q7PVT4_ANOGA
AGAP009189-PA.
   
 0.990
Q7QG29_ANOGA
Cyclin G-associated kinase.
   
 0.984
Q7Q0T8_ANOGA
AGAP010167-PA.
    
 0.979
Q7PQY9_ANOGA
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
   
 0.961
A7URE8_ANOGA
AGAP007396-PA.
   
 0.957
Q7QF64_ANOGA
Adaptin ear-binding coat-associated protein 1.
    
 0.956
Q5TSE5_ANOGA
Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.
    
 0.951
Your Current Organism:
Anopheles gambiae
NCBI taxonomy Id: 7165
Other names: A. gambiae, African malaria mosquito, Anopheles gambiae S, Anopheles gambiae sensu stricto
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