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STRINGSTRING
ebo protein (fruit fly) - STRING interaction network
"ebo" - Ellipsoid body open in Drosophila melanogaster
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eboEllipsoid body open (Ebo) complexes with actin, chic, and Ran-GTPase to mediate actin nuclear export. Loss of Ebo during development results in defects in the ellipsoid body of the central complex. In the adult brain, accumulation of nuclear actin results in bs inhibition and subsequent loss of visual orientation memory (1047 aa)    
Predicted Functional Partners:
ewg
DNA-binding protein Ewg; May function as a positive regulator of transcription in developing and differentiated neurons, regulating common aspects of neuronal differentiation and maintenance. Requirement in the CNS may be higher than in the peripheral system. Vital for development of the indirect flight muscles; Belongs to the NRF1/Ewg family (843 aa)
     
   
  0.826
Gint3
GDI interacting protein 3, isoform B; Protein binding (441 aa)
     
      0.811
Cas
Exportin-2; Export receptor for importin alpha. Mediates importin- alpha re-export from the nucleus to the cytoplasm after import substrates have been released into the nucleoplasm (By similarity) (975 aa)
     
 
  0.804
Ranbp16
Ran-binding protein 16; May function as a nuclear transport receptor (1110 aa)
     
 
  0.793
Ran-like
GTP-binding nuclear protein Ran-like; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export (217 aa)
     
 
  0.789
Ran
GTP-binding nuclear protein Ran; GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs. Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis. Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP-bound Ran and release them upon direct interaction with GTP-bound Ran while export receptors behave in the opposite way. Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment a [...] (216 aa)
     
 
  0.789
Ranbp9
Ran GTPase binding. It is involved in the biological process described with- intracellular protein transport (1018 aa)
     
 
  0.788
CG5955
GH18546p; UDP-glucose 4-epimerase activity; coenzyme binding (367 aa)
       
 
  0.779
CG31320
Dynein assembly factor 5, axonemal; Cytoplasmic protein involved in the delivery of the dynein machinery to the motile cilium. It is required for the assembly of the axonemal dynein inner and outer arms, two structures attached to the peripheral outer doublet A microtubule of the axoneme, that play a crucial role in cilium motility (845 aa)
       
      0.756
CstF-50
LD24780p; It is involved in the biological process described with- mRNA cleavage (424 aa)
       
      0.720
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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