STRINGSTRING
Exp6 protein (fruit fly) - STRING interaction network
"Exp6" - Exportin 6 in Drosophila melanogaster
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Exp6Exportin 6 (1047 aa)    
Predicted Functional Partners:
Ran-like
Ran-like; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export (217 aa)
     
  0.953
Ran
Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. RanGTP modulates both spindle and nuclear envelope assembly supporting a mitotic role of Ran (216 aa)
     
  0.953
Nup358
Nucleoporin 358 (2718 aa)
     
  0.924
RanGAP
Ran GTPase activating protein; GTPase activator for the nuclear Ras-related regulatory protein Ran, converting it to the putatively inactive GDP-bound state (By similarity). Trans-acting factor necessary for meiotic distortion. Distortion is only seen in individuals that carry the RanGAP tandem duplication and express a RanGAP truncated protein. Binding of truncated RanGAP product to the Responder(RSP) locus initiates events that lead to sperm dysfunction (596 aa)
     
  0.923
CG5394
Glutamyl-prolyl-tRNA synthetase; Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction- the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA (1714 aa)
     
 
  0.883
RanBP3
Ran binding protein 3 (449 aa)
       
 
  0.836
Nup153
Nucleoporin 153; Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC. Essential for the nuclear import of nuclear localization signal (NLS)-containing proteins in a Importin alpha/Importin beta receptor-dependent manner. Plays a role in chromosomal organization and gene expression regulation; stimulates transcription by promoting the formation of an open chromatin environment. Binds chromatin to nucleoporin-associated regions (NARs) that define transcriptional [...] (1929 aa)
     
  0.826
Nup214
Nucleoporin 214; May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex (1711 aa)
       
  0.772
Dbp80
Dead box protein 80; ATP-dependent RNA helicase involved in mRNA export from the nucleus (481 aa)
     
 
  0.750
CG42303
Snurportin (351 aa)
     
 
  0.711
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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