• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
Cyp4g1 protein (fruit fly) - STRING interaction network
"Cyp4g1" - Cytochrome P450-4g1 in Drosophila melanogaster
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cyp4g1Cytochrome P450-4g1 (Cyp4g1) is an essential lipid gamma-hydroxylase that regulates triacylglycerol composition in the oenocytes. Roles of Cyp4g1 include lipid metabolism and cuticular hydrocarbon synthesis (556 aa)    
Predicted Functional Partners:
pcl
Pepsinogen-like is predicted to belong to a family of aspartic proteases and controls planar cell polarity. Its mutations cause loss of wing margins; Belongs to the peptidase A1 family (407 aa)
           
  0.699
CG7910
CG7910, isoform A; Fatty acid amide hydrolase activity; carbon-nitrogen ligase activity, with glutamine as amido-N-donor. It is involved in the biological process described with- regulation of cell cycle (530 aa)
     
        0.647
Cpr
NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome p450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome b5 (By similarity). May function to clear the olfactory organ (antennae) from accumulating chemicals; In the N-terminal section; belongs to the flavodoxin family (679 aa)
 
 
  0.613
CG15531
Uncharacterized protein; stearoyl-CoA 9-desaturase activity. It is involved in the biological process described with- oxidation-reduction process; lipid metabolic process; Belongs to the fatty acid desaturase type 1 family (334 aa)
     
 
  0.594
Mdr50
Multi drug resistance 50; ATPase activity, coupled to transmembrane movement of substances; ATP binding; drug transmembrane transporter activity; ATPase activity, coupled. It is involved in the biological process described with- response to methotrexate; drug transport; transmembrane transport (1313 aa)
           
  0.553
v(2)k05816
Fatty acid synthase 2 is required for the synthesis of branched/methylated long chain fatty acids that are the precursors of methylated cuticular hydrocarbons (2409 aa)
   
 
  0.550
pio
Piopio, isoform B; It is involved in the biological process described with- chitin-based cuticle attachment to epithelium; chitin-based embryonic cuticle biosynthetic process; apposition of dorsal and ventral imaginal disc-derived wing surfaces; open tracheal system development (462 aa)
           
  0.543
CG17568
IP01252p; Zinc ion binding; nucleic acid binding (513 aa)
       
 
  0.508
CG1444
RH59310p; Steroid dehydrogenase activity. It is involved in the biological process described with- metabolic process; Belongs to the short-chain dehydrogenases/reductases (SDR) family (321 aa)
   
   
  0.506
Desat1
Desaturase 1 (Desat1) is a transmembrane fatty acid desaturase that utilizes myristate and stearate (C16-0 and C18-0) to synthesize myristoleic and oleic acids (C16-1 and C18-1). Desat1 is involved in the synthesis of unsaturated fatty acids (383 aa)
     
 
  0.489
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
Server load: low (9%) [HD]