STRINGSTRING
CG13364 protein (fruit fly) - STRING interaction network
"CG13364" - Coiled-coil domain-containing protein 72 homolog in Drosophila melanogaster
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG13364Coiled-coil domain-containing protein 72 homolog (64 aa)    
Predicted Functional Partners:
RpL29
Chromatin binding (76 aa)
     
        0.984
CG7048
Unfolded protein binding; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity) (168 aa)
     
        0.888
CG7637
snoRNP protein dNop10; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs (By similarity) (64 aa)
     
        0.886
Nedd8
Nedd8; Ubiquitin-like protein which plays an important role in cell cycle control, embryogenesis and neurogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex Uba3-Ula1 and linkage to the E2 enzyme Ubc12. Attachment of Nedd8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins (84 aa)
     
        0.878
mRpL33
Structural constituent of ribosome (64 aa)
     
        0.877
SmG
Small ribonucleoprotein particle protein SmG; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5 (76 aa)
     
        0.860
Spase12
Spase 12-subunit; Microsomal signal peptidase is a membrane-bound endoproteinase that removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (98 aa)
     
        0.846
CG8860
Protein transporter activity; Necessary for protein translocation in the endoplasmic reticulum (68 aa)
     
        0.802
mRpL14
Structural constituent of ribosome (161 aa)
     
        0.799
e(y)2
Enhancer of yellow 2; Involved in mRNA export coupled transcription activation by association with both the AMEX and the SAGA complexes. The SAGA complex is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Involved in transcription elongati [...] (101 aa)
     
        0.798
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
Server load: high (87%) [HD]