STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG14630Uncharacterized protein; Gamma-butyrobetaine dioxygenase activity. It is involved in the biological process described with: carnitine biosynthetic process; oxidation-reduction process. (406 aa)    
Predicted Functional Partners:
CG10184
LD34157p; L-allo-threonine aldolase activity. It is involved in the biological process described with: threonine catabolic process; glycine biosynthetic process.
   
  
 0.934
CG6356
FI05810p; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport.
      
 0.602
colt
Congested-like trachea protein; Putative mitochondrial carrier of unknown solute specificity. Required for gas-filling of the tracheal system at hatching time of the embryo and for normal epithelial morphogenesis of the wings.
   
  
 0.503
CG5265
Carn_acyltransf domain-containing protein; Carnitine O-acetyltransferase activity. It is involved in the biological process described with: carnitine metabolic process; carnitine metabolic process, CoA-linked; fatty acid metabolic process; Belongs to the carnitine/choline acetyltransferase family.
      
 0.503
Balat
Beta-alanine transporter; Beta-alanine transporter required for the uptake of beta- alanine by the glia. Required for the recycling process of the neurotransmitter histamine in photoreceptor neurons of the compound eye and therefore for photoreceptor synaptic transmission. Following histamine release from photoreceptors and its uptake by glia, histamine is conjugated to beta-alanine by e/Ebony to form the inactive metabolite, carcinine.
      
 0.470
SLC22A
SLC22A family member (SLC22A) encodes a plasma membrane transporter and a member of the conserved family of SLC22A transporters. The product of SLC22A is preferentially localized in the dendrites of mushroom body neurons, where it functions to terminate synaptic transmission from cholinergic projection neurons through uptake of the released neurotransmitter acetylcholine. Impairing the function of SLC22A enhances the acquisition and retention of olfactory memory by allowing the neurotransmitter signal from projection neurons to be more persistent.
      
 0.430
CPT2
Carnitine palmitoyltransferase 2 (CPT2) encodes an enzyme required for the beta-oxidation of long-chain fatty acids; Belongs to the carnitine/choline acetyltransferase family.
   
  
 0.400
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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