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TfIIA-S-2 protein (fruit fly) - STRING interaction network
TfIIA-S-2 in Drosophila melanogaster
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
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TfIIA-S-2TfIIA-S-2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity (By similarity) (107 aa)    
Predicted Functional Partners:
TfIIB
Transcription factor IIB; General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II (315 aa)
     
  0.995
RpII33
DNA binding (275 aa)
     
  0.991
TfIIFbeta
Transcription factor TFIIFbeta; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA- helicase activity (By similarity) (277 aa)
     
  0.991
Tfb5
TFB5 ortholog (S. cerevisiae) (73 aa)
     
    0.990
mrn
Marionette (499 aa)
       
  0.990
TfIIEalpha
Sequence-specific DNA binding (429 aa)
     
  0.990
Tbp
TATA binding protein; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre- initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II (353 aa)
     
  0.990
RpII18
RNA polymerase II 18kD subunit; DNA-dependent RNA polymerases catalyze the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, RPB6 is part of the clamp element and together with par [...] (131 aa)
     
    0.989
Rpb4
Protein binding; DNA-directed RNA polymerase activity; chromatin binding; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Associates with POLR2G (139 aa)
     
    0.989
TfIIEbeta
Transcription factor IIEbeta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase (292 aa)
     
  0.989
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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