STRINGSTRING
CG3719 protein (fruit fly) - STRING interaction network
"CG3719" - Disulfide oxidoreductase activity in Drosophila melanogaster
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG3719Disulfide oxidoreductase activity (160 aa)    
Predicted Functional Partners:
Prx3
Peroxiredoxin 3 (234 aa)
   
  0.979
Prx5
Peroxiredoxin 5 (190 aa)
   
  0.972
Trxr-1
Thioredoxin reductase-1; Thioredoxin system is a major player in glutathione metabolism, due to the demonstrated absence of a glutathione reductase. Functionally interacts with the Sod/Cat reactive oxidation species (ROS) defense system and thereby has a role in preadult development and life span. Lack of a glutathione reductase suggests antioxidant defense in Drosophila, and probably in related insects, differs fundamentally from that in other organisms (596 aa)
   
  0.968
CG9674
Glutamate synthase (NADPH) activity (2115 aa)
   
 
  0.967
Trxr-2
Thioredoxin reductase 2; Thioredoxin system is a major player in glutathione metabolism, due to the demonstrated absence of a glutathione reductase. Functionally interacts with the Sod/Cat reactive oxidation species (ROS) defense system and thereby has a role in preadult development and life span. Lack of a glutathione reductase suggests antioxidant defense in Drosophila, and probably in related insects, differs fundamentally from that in other organisms (516 aa)
   
  0.965
CG8993
Disulfide oxidoreductase activity (142 aa)
   
   
0.914
CG8517
Disulfide oxidoreductase activity (145 aa)
   
   
 
0.908
CG6888
Thioredoxin peroxidase activity (196 aa)
   
 
  0.904
Jafrac2
Thioredoxin peroxidase 2 (242 aa)
   
 
  0.806
Jafrac1
Thioredoxin peroxidase 1; Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. As a reducing substrate, thioredoxin 2 is preferred over thioredoxin 1 (194 aa)
   
 
  0.777
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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