STRINGSTRING
png protein (fruit fly) - STRING interaction network
"png" - Pan gu in Drosophila melanogaster
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pngPan gu (291 aa)    
Predicted Functional Partners:
gnu
Giant nuclei (240 aa)
     
 
  0.943
plu
Plutonium; Inhibits DNA replication early in developments. May bind and block the action of a replication or initiation factor (174 aa)
     
 
  0.898
CycB
Cyclin B; Essential for the control of the cell cycle at the G2/M (mitosis) transition (530 aa)
     
  0.885
CycA
Cyclin A; Essential for the control of the cell cycle at the G2/M (mitosis) transition. Interacts with the Cdk1 and Cdk2 protein kinases to form MPF. G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis (491 aa)
     
  0.865
CycE
Cyclin E; Essential for the control of the cell cycle at the G1/S (start) transition. Targeted by archipelago for degradation by the SFC ubiquitin ligase complex (712 aa)
     
  0.819
Cdk7
Cyclin-dependent kinase 7 (353 aa)
   
 
0.800
Pka-C2
cAMP-dependent protein kinase 2 (354 aa)
   
 
0.765
CG12069
Protein serine/threonine kinase activity (356 aa)
   
 
0.765
Pka-C3
cAMP-dependent protein kinase 3; Does not have an essential role in development (583 aa)
   
 
0.760
Pka-C1
Protein binding (353 aa)
   
 
0.758
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
Server load: medium (45%) [HD]