STRINGSTRING
pck protein (fruit fly) - STRING interaction network
"pck" - Pickel in Drosophila melanogaster
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pckPickel (256 aa)    
Predicted Functional Partners:
mt:CoI
Cytochrome-c oxidase activity; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B (511 aa)
           
  0.733
mus205
Mutagen-sensitive 205 (2130 aa)
           
  0.579
CG6768
DNA polymerase epsilon (2236 aa)
           
  0.579
sea
Scheggia (317 aa)
           
  0.507
mt:Cyt-b
Mitochondrial Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (378 aa)
           
  0.497
mt:ND4L
NADH dehydrogenase (ubiquinone) activity; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity) (96 aa)
           
  0.495
mt:ND5
NADH dehydrogenase (ubiquinone) activity; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity) (574 aa)
           
  0.495
DNaseII
Deoxyribonuclease II (366 aa)
           
  0.495
mt:ND2
NADH dehydrogenase (ubiquinone) activity; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity) (341 aa)
           
  0.483
Klp61F
Motor activity; Important role in mitotic dividing cells (PubMed-8227131). Microtubule motor required for spindle body separation (PubMed-8918872). Slow plus-end directed microtubule motor capable of cross-linking and sliding apart antiparallel microtubules, thereby pushing apart the associated spindle poles during spindle assembly and function (PubMed-8918872, PubMed-8589456, PubMed-19062285). Forms cross-links between microtubules within interpolar microtubule bundles (PubMed-9885249, PubMed-19158379). Contributes to the length of the metaphase spindle, maintains the prometaphase spi [...] (1066 aa)
     
   
  0.479
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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