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Ns3 protein (fruit fly) - STRING interaction network
"Ns3" - GTP binding in Drosophila melanogaster
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Ns3GTP binding; GTPase required for the nuclear export of the 60S ribosomal subunit. Probably acts by mediating the release of Nmd3 from the 60S ribosomal subunit after export into the cytoplasm. Regulator of body size; acts in serotonergic neurons to regulate insulin signaling and thus exerts global growth control (606 aa)    
Predicted Functional Partners:
Nmd3
mRNA binding (521 aa)
     
 
  0.990
CG4364
Pescadillo homolog ; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit (627 aa)
     
 
  0.985
CG8801
GTP binding; Involved in the biogenesis of the 60S ribosomal subunit (By similarity). Required for normal assembly of the mitotic spindle (PubMed-24255106). May be involved in both centrosome- dependent and centrosome-independent spindle assembly programs (PubMed-24255106) (652 aa)
     
 
  0.972
pen
Penguin (737 aa)
     
      0.969
CG6937
mRNA binding (356 aa)
     
 
  0.966
CG1542
Probable rRNA-processing protein EBP2 homolog; Required for the processing of the 27S pre-rRNA (307 aa)
     
 
  0.966
CG5033
Ribonucleoprotein complex binding; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit (784 aa)
     
 
  0.950
l(1)G0020
Lethal (1) G0020; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)- acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation (Probable). Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptional [...] (1008 aa)
     
        0.948
CG10576
Aminopeptidase activity (391 aa)
   
 
  0.948
Mys45A
Mystery 45A; Required for 60S pre-ribosomal subunits export to the cytoplasm (712 aa)
     
 
  0.948
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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