STRINGSTRING
Ocrl protein (fruit fly) - STRING interaction network
"Ocrl" - Oculocerebrorenal syndrome of Lowe 1 ortholog in Drosophila melanogaster
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OcrlOculocerebrorenal syndrome of Lowe 1 ortholog (850 aa)    
Predicted Functional Partners:
CG10260
Phosphatidylinositol 4-kinase III alpha (2154 aa)
     
  0.968
fwd
Four wheel drive (1674 aa)
     
  0.956
Eps-15
Calcium ion binding (1253 aa)
     
  0.954
sktl
Skittles (792 aa)
     
  0.953
drk
Downstream of receptor kinase; Required for proper signaling by sevenless. May act to stimulate the ability of Sos to catalyze Ras1 activation by linking sevenless and Sos in a signaling complex (211 aa)
       
  0.948
CG17471
1-phosphatidylinositol-4-phosphate 5-kinase activity (404 aa)
     
  0.947
synj
Synaptojanin (1218 aa)
     
0.946
lqf
Liquid facets (831 aa)
     
  0.945
lap
like-AP180; Assembly protein recruiting clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. May be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. Involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction (788 aa)
     
 
  0.945
Pi3K92E
Pi3K92E (1088 aa)
     
  0.942
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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