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CG4406 protein (fruit fly) - STRING interaction network
"CG4406" - GPI-anchor transamidase activity in Drosophila melanogaster
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
Coexpression
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[Homology]
Score
CG4406GPI-anchor transamidase activity; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein’s C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein (By similarity) (355 aa)    
Predicted Functional Partners:
CG11190
RE52151p (633 aa)
     
  0.998
CG3033
Glycosylphosphatidylinositol anchor attachment 1 ortholog (H. sapiens) (674 aa)
     
  0.996
CG13089
Phosphatidylinositol glycan anchor biosynthesis, class U ortholog (H. sapiens) (426 aa)
     
  0.986
CG31120
Phosphatidylinositol glycan anchor biosynthesis, class S ortholog (H. sapiens) (EC-3.-.-.-) (536 aa)
     
  0.985
CG12263
Catalytic activity (1077 aa)
     
  0.958
CG9376
CG9376 (236 aa)
     
 
  0.934
CG3160
Phosphoric ester hydrolase activity; nuclease activity; Involved in inositol deacylation of GPI-anchored proteins (980 aa)
     
  0.912
CG2144
Catalytic activity (927 aa)
     
 
  0.658
CG3800
Nucleic acid binding (165 aa)
 
            0.629
CG14872
Uncharacterized protein (310 aa)
           
  0.575
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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