STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pex5Peroxin 5, isoform A; Peroxisome matrix targeting signal-1 binding. It is involved in the biological process described with: protein import into peroxisome matrix, docking; response to anesthetic; peroxisome organization. (614 aa)    
Predicted Functional Partners:
Pex7
Peroxin 7, isoform A; Peroxisome matrix targeting signal-2 binding. It is involved in the biological process described with: peroxisome organization; protein import into peroxisome matrix.
    
 0.999
Pex14
Peroxin 14; Signaling receptor binding. It is involved in the biological process described with: protein targeting to peroxisome; peroxisome organization; protein import into peroxisome matrix, docking.
   
 0.999
ScpX
Sterol carrier protein X-related thiolase; Transferase activity, transferring acyl groups other than amino-acyl groups; phospholipid transporter activity. It is involved in the biological process described with: positive regulation of intracellular cholesterol transport; phospholipid transport; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.999
Pex13
Peroxin 13 (Pex13) encodes a peroxisome protein important for sperm development.
   
 0.998
Pex12
Peroxin 12 (Pex12) encodes a peroxisome protein important for sperm development; Belongs to the pex2/pex10/pex12 family.
   
 0.997
Pex10
Peroxin 10 (Pex10) encodes a peroxisome protein important for sperm development.
   
 0.993
Pex6
Peroxin 6, isoform D; ATP binding; ATPase activity. It is involved in the biological process described with: peroxisome organization; protein import into peroxisome matrix; protein targeting to peroxisome.
   
 
 0.985
Hacl
Magnesium ion binding; carbon-carbon lyase activity; thiamine pyrophosphate binding. It is involved in the biological process described with: fatty acid alpha-oxidation; Belongs to the TPP enzyme family.
 
 
 0.978
Pex19
Peroxin 19, isoform A; Peroxisome membrane targeting sequence binding. It is involved in the biological process described with: nervous system development; protein import into peroxisome membrane; peroxisome organization.
   
 
 0.961
Pex11
Peroxin 11; It is involved in the biological process described with: regulation of peroxisome size; peroxisome fission; peroxisome organization.
   
 
 0.950
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.