STRINGSTRING
Mct1 protein (fruit fly) - STRING interaction network
"Mct1" - Monocarboxylate transporter 1 in Drosophila melanogaster
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mct1Monocarboxylate transporter 1 (626 aa)    
Predicted Functional Partners:
CG9674
Glutamate synthase (NADPH) activity (2115 aa)
   
   
  0.595
ATPCL
ATP citrate lyase; ATP-citrate synthase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues (1112 aa)
   
   
  0.571
Rad51C
Rad51C (336 aa)
   
   
  0.565
r-l
Rudimentary-like (493 aa)
         
  0.545
su(r)
Suppressor of rudimentary (1031 aa)
   
   
  0.543
spn-D
Spindle D (270 aa)
   
   
  0.536
Top2
Topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands (PubMed-6308011, PubMed-2547764, PubMed-1328202, PubMed-8383533, PubMed-10786800, PubMed-8978614). Topoisomerase II makes double-strand breaks (PubMed-6308011, PubMed-2547764, PubMed-1328202, PubMed-8383533, PubMed-10786800, PubMed-9545289). Essential during mitosis and meiosis for proper segregation of daughter chromosomes (PubMed-10751154, PubMed-14600258, PubMed-18752348, PubMed-25340780). During meiosis, it disrupts heterochromatic connections between achiasmate and c [...] (1447 aa)
   
   
  0.527
r
Rudimentary; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) (2224 aa)
   
   
  0.518
P58IPK
P58IPK (498 aa)
   
 
  0.518
CG1140
3-oxoacid CoA-transferase activity; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate (516 aa)
         
  0.507
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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