STRINGSTRING
Ilp6 protein (fruit fly) - STRING interaction network
"Ilp6" - Insulin-like peptide 6 in Drosophila melanogaster
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ilp6Insulin-like peptide 6 (107 aa)    
Predicted Functional Partners:
Ilp5
Insulin-like peptide 5 (107 aa)
         
  0.970
Ilp3
Insulin-like peptide 3 (120 aa)
         
  0.969
Ilp2
Insulin-like peptide 2; Plays a role in regulating body size by increasing cell size and cell number of individual organs. Probably mediates its growth effects by acting as a ligand for the insulin receptor and transducing a signal via the Chico/PI3K/Akt(PKB) pathway (137 aa)
         
  0.960
Ilp7
Insulin-like peptide 7 (159 aa)
         
  0.951
Ilp1
Insulin-like peptide 1 (154 aa)
         
  0.945
Ilp4
Insulin-like peptide 4 (134 aa)
         
  0.895
InR
Insulin-like receptor; Has a ligand-stimulated tyrosine-protein kinase activity. Required for cell survival. Regulates body size and organ size by altering cell number and cell size in a cell- autonomous manner. Involved in the development of the embryonic nervous system, and is necessary for axon guidance and targeting in the visual system. Also plays a role in life-span determination (2144 aa)
         
  0.885
upd2
Unpaired 2 (370 aa)
           
  0.495
ImpL2
Ecdysone-inducible gene L2; Essential developmental role during embryogenesis, in particular the normal development of the nervous system. May be involved in some aspect of cell adhesion (267 aa)
           
  0.480
CG2854
CG2854 (491 aa)
           
  0.475
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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