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STRINGSTRING
crn protein (fruit fly) - STRING interaction network
"crn" - Protein crooked neck in Drosophila melanogaster
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crnProtein crooked neck; May be involved in pre-mRNA splicing process. Involved in neurogenesis; Belongs to the crooked-neck family (702 aa)    
Predicted Functional Partners:
CG6015
LD21931p; It is involved in the biological process described with- mRNA splicing, via spliceosome (576 aa)
     
  0.999
CG9667
CG9667, isoform A; It is involved in the biological process described with- mRNA splicing, via spliceosome (272 aa)
     
  0.999
Cdc5
Cell division cycle 5, isoform A; DNA binding; chromatin binding. It is involved in the biological process described with- mRNA splicing, via spliceosome; centrosome duplication (814 aa)
     
  0.999
Bx42
Puff-specific protein Bx42; May play a role in chromatin structure and function (547 aa)
     
  0.999
fand
FI18620p1; It is involved in the biological process described with- phagocytosis; RNA splicing; regulation of alternative mRNA splicing, via spliceosome; mRNA splicing, via spliceosome (883 aa)
     
0.999
CG4849
LD28793p; GTPase activity; translation elongation factor activity; GTP binding. It is involved in the biological process described with- translational elongation; positive regulation of Ras protein signal transduction; positive regulation of ERK1 and ERK2 cascade; mRNA splicing, via spliceosome (975 aa)
     
  0.999
CG12343
Pre-mRNA-splicing factor Syf2; May be involved in pre-mRNA splicing (226 aa)
     
  0.998
Tango4
Transport and golgi organization 4; It is involved in the biological process described with- protein secretion; mRNA splicing, via spliceosome; Golgi organization (482 aa)
     
  0.998
Prp8
Pre-mRNA processing factor 8 (Prp8) is an essential gene that encodes the largest and most highly conserved splicing factor. Prp8 is a core component of the U5 snRNP, with a key function in pre-mRNA processing catalyzed by the spliceosome (2396 aa)
     
  0.998
Prp19
Pre-RNA processing factor 19; Ubiquitin-protein transferase activity. It is involved in the biological process described with- positive regulation of Ras protein signal transduction; regulation of alternative mRNA splicing, via spliceosome; positive regulation of ERK1 and ERK2 cascade; mRNA splicing, via spliceosome; protein ubiquitination (505 aa)
     
  0.998
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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