STRINGSTRING
msta protein (fruit fly) - STRING interaction network
"msta" - Msta in Drosophila melanogaster
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mstaMsta (462 aa)    
Predicted Functional Partners:
Br140
Zinc ion binding (1430 aa)
     
 
  0.591
CG7220
Ubiquitin-protein ligase activity (190 aa)
     
 
  0.584
Set2
Set2; Probable histone methyltransferase. Histone methylation gives specific tags for epigenetic transcriptional activation or repression (By similarity) (2362 aa)
     
   
  0.539
Set1
Histone methyltransferase activity (H3-K4 specific); Catalytic component of the SET1 complex that specifically di- and trimethylates ’Lys-4’ of histone H3 and is the main di- and trimethyltransferase thoughout development. Set1- dependent trimethylation regulates chromatin changes at active promoters that ensure optimal RNA polymerase II release into productive elongation, thereby contributing to optimal transcription (1641 aa)
     
 
  0.532
CG6656
Acid phosphatase activity (395 aa)
     
   
  0.525
ash2
Zinc ion binding; Transcriptional regulator. Regulates a number of genes involved in wing development including activation of net and bs and repression of rho and kni and controls vein-intervein patterning during wing development. Required for correct expression of a number of homeotic genes including Scr in the first leg imaginal disk and Ubx in the third leg imaginal disk and haltere disks. Required for stabilization of the histone-lysine N- methyltransferase trr and for trimethylation of ’Lys-4’ of histone H3. Plays a role in maintenance of transcriptionally active chromatin through [...] (556 aa)
     
 
  0.520
esc
Extra sexcombs; Polycomb group (PcG) protein. While PcG proteins are generally required to maintain the transcriptionally repressive state of homeotic genes throughout development, this protein is specifically required during the first 6 hours of embryogenesis to establish the repressed state. Component of the Esc/E(z) complex, which methylates ’Lys-9’ and ’Lys-27’ residues of histone H3, leading to transcriptional repression of the affected target gene. The Esc/E(z) complex is necessary but not sufficient for the repression of homeotic target genes, suggesting that the recruitment of [...] (425 aa)
     
  0.512
escl
Escl (462 aa)
     
  0.512
MBD-R2
MBD-R2 (1169 aa)
       
 
  0.509
upSET
Core promoter binding (3146 aa)
       
 
  0.507
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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