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CG16903 protein (fruit fly) - STRING interaction network
"CG16903" - Cyclin-dependent protein serine/threonine kinase regulator activity in Drosophila melanogaster
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
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[Homology]
Score
CG16903Cyclin-dependent protein serine/threonine kinase regulator activity (560 aa)    
Predicted Functional Partners:
cdc2rk
Cdc2-related-kinase (387 aa)
     
 
  0.918
Pitslre
Pitslre; Acts as a negative regulator of the normal cell cycle progression. May function in regulating proliferation by the phosphorylation and subsequent plasma membrane targeting of galactosyltransferase (By similarity) (952 aa)
     
 
  0.911
Mat1
Mat1 (320 aa)
     
  0.870
Cdk12
RNA polymerase II carboxy-terminal domain kinase activity; Cyclin-dependent kinase which displays CTD kinase activity- hyperphosphorylates the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit, thereby acting as a key regulator of transcription elongation (1157 aa)
     
 
  0.862
Cdk7
Cyclin-dependent kinase 7 (353 aa)
     
  0.858
CG6800
Cyclin-dependent protein serine/threonine kinase activity (302 aa)
     
  0.848
Cdk9
Cyclin-dependent kinase 9 (404 aa)
     
 
  0.804
Cdk8
Cyclin-dependent kinase 8; Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May phosphorylate the CTD (C-terminal domain) of the [...] (454 aa)
     
 
  0.774
Cdk4
Cyclin binding (317 aa)
     
  0.682
TfIIEbeta
Transcription factor IIEbeta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase (292 aa)
       
 
  0.664
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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