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CG2681 protein (fruit fly) - STRING interaction network
"CG2681" - Ubiquitin-protein ligase activity in Drosophila melanogaster
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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CG2681Ubiquitin-protein ligase activity; zinc ion binding; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates (626 aa)    
Predicted Functional Partners:
Ubc84D
Ubiquitin conjugating enzyme 84D; Catalyzes the covalent attachment of ubiquitin to other proteins (153 aa)
       
 
  0.550
UbcD6
Ubiquitin conjugating enzyme; Catalyzes the covalent attachment of ubiquitin to other proteins. Required for postreplication repair of UV-damaged DNA (151 aa)
     
 
  0.550
UbcD4
Ubiquitin conjugating enzyme 4; Catalyzes the covalent attachment of ubiquitin to other proteins (199 aa)
       
 
  0.508
CG11700
Uncharacterized protein (301 aa)
       
 
  0.506
RpS27A
Ribosomal protein S27A; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked- Lys-48-linked is involved in protein d [...] (156 aa)
       
 
  0.506
RpL40
Ribosomal protein L40; Ubiquitin- exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked- Lys-48-linked is involved in protein d [...] (128 aa)
       
 
  0.506
Ubi-p63E
Ubiquitin-63E; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked- Lys-48-linked is involved in protein degradatio [...] (763 aa)
       
 
  0.506
Ubi-p5E
Ubiquitin-5E (534 aa)
       
 
  0.506
UbcD2
Ubiquitin conjugating enzyme 2; Catalyzes the covalent attachment of ubiquitin to other proteins (232 aa)
       
 
  0.502
eff
Effete; Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. Required for proper telomere behavior during cell divisions and possibly for ubiquitination of proteins involved in postmeiotic stages of spermatogenesis. Deletion mutations are lethal in homozygotes (147 aa)
       
 
  0.500
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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