STRINGSTRING
CG2658 protein (fruit fly) - STRING interaction network
"CG2658" - Metallopeptidase activity in Drosophila melanogaster
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
CG2658Metallopeptidase activity; ATPase activity (819 aa)    
Predicted Functional Partners:
l(2)37Cc
Lethal (2) 37Cc; Required for larval metabolism or for the progression of the larva into a pupa (276 aa)
   
 
  0.878
l(2)03709
Lethal (2) 03709 (338 aa)
   
 
  0.856
pug
Pugilist (968 aa)
   
   
  0.753
r
Rudimentary; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) (2224 aa)
   
 
  0.744
Aats-phe
Phenylalanyl-tRNA synthetase; Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation (453 aa)
   
 
  0.708
blw
Bellwether; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proto [...] (552 aa)
     
 
  0.706
CG3499
ATP-dependent peptidase activity (740 aa)
   
 
0.672
Lon
Lon protease; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner. Regulates mitochondrial DNA (mtDNA) copy number and transcription by stabilizing the mitoch [...] (1024 aa)
   
 
  0.638
CG5394
Glutamyl-prolyl-tRNA synthetase; Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction- the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA (1714 aa)
   
 
  0.621
ATPCL
ATP citrate lyase; ATP-citrate synthase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues (1112 aa)
   
   
  0.601
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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