STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG4593CG4593-PA. (209 aa)    
Predicted Functional Partners:
CG12684
IP21517p.
      
 0.913
CG7387
Unfolded protein binding; heat shock protein binding. It is involved in the biological process described with: regulation of apoptotic process; protein folding; mitochondrion organization.
      
 0.913
CG15336
Uncharacterized protein; Sequence-specific DNA binding.
      
 0.910
CG11379
EG:BACR42I17.4 protein.
      
 0.910
CG7840
Polyprenol reductase; Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N- glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism (By similarity).
   
  
 0.862
CG13690
Ribonuclease H2 subunit A; Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes (By similarity).
   
  
 0.846
CG15717
CG15717-PA; Oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process.
   
  
 0.845
CG9135
CG9135 protein; It is involved in the biological process described with: negative regulation of GTPase activity.
   
  
 0.842
CG10853
CG10853-PA.
      
 0.836
CG2577
CG2577-PA; Protein serine/threonine kinase activity; ATP binding. It is involved in the biological process described with: peptidyl-serine phosphorylation; Wnt signaling pathway.
      
 0.790
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.