STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Inx7Innexin 7 (Inx7) is one out of eight gap junction protein encoding genes in Drosophila. It is expressed in all embryonic epithelia from early to late stages of development and is found in glial and neuronal cells. It is functionally required for embryonic nervous system development; Belongs to the pannexin family. (438 aa)    
Predicted Functional Partners:
Tsp42Ec
Tetraspanin.
   
  
 0.700
CG4301
ATPase-coupled intramembrane lipid transporter activity; ATP binding; magnesium ion binding. It is involved in the biological process described with: phospholipid translocation; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
   
 
 0.688
CG5096
RE59088p.
   
  
 0.679
CG10300
CRAL-TRIO domain-containing protein; Phosphatidylinositol bisphosphate binding.
   
  
 0.660
Tsp29Fa
Tetraspanin.
   
  
 0.627
CG33127
IP10114p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
   
 
 0.621
CG4781
RE54577p.
   
  
 0.582
Tsp42Er
Tetraspanin.
   
  
 0.579
CG1246
RE02644p.
   
    0.574
CG14856
FI01439p; Transmembrane transporter activity. It is involved in the biological process described with: transmembrane transport.
   
  
 0.506
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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