node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cyp305a1 | sni | FBpp0074694 | FBpp0311239 | Probable cytochrome P450 305a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | Sniffer, isoform A; Sniffer (sni) encodes a homodimeric carbonyl reductase that belongs to the SDR superfamily of proteins. It catalyzes the reduction of the lipid derived aldehyde 4-oxononenal. It contributes to protection against oxidative stress-induced neurodegeneration and prevention of apoptosis by removal of damaged cardiolipin; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.516 |
Cyp309a1 | Ugt37A3 | FBpp0307161 | FBpp0291574 | Probable cytochrome P450 309a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | UDP-glycosyltransferase family 37 member A3; Transferase activity, transferring hexosyl groups; UDP-glycosyltransferase activity. | 0.699 |
Cyp309a1 | sni | FBpp0307161 | FBpp0311239 | Probable cytochrome P450 309a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | Sniffer, isoform A; Sniffer (sni) encodes a homodimeric carbonyl reductase that belongs to the SDR superfamily of proteins. It catalyzes the reduction of the lipid derived aldehyde 4-oxononenal. It contributes to protection against oxidative stress-induced neurodegeneration and prevention of apoptosis by removal of damaged cardiolipin; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.451 |
Cyp6d2 | Ugt37A3 | FBpp0071839 | FBpp0291574 | Cyp6d2 (Cyp6d2) encodes a member of the cytochrome P450 oxidase protein family and is involved in the detoxification of toxic compounds. Two common Cyp6d2 alleles found in many Dmel stocks result in extreme sensitivity to camptothecin. | UDP-glycosyltransferase family 37 member A3; Transferase activity, transferring hexosyl groups; UDP-glycosyltransferase activity. | 0.635 |
Cyp6d2 | sni | FBpp0071839 | FBpp0311239 | Cyp6d2 (Cyp6d2) encodes a member of the cytochrome P450 oxidase protein family and is involved in the detoxification of toxic compounds. Two common Cyp6d2 alleles found in many Dmel stocks result in extreme sensitivity to camptothecin. | Sniffer, isoform A; Sniffer (sni) encodes a homodimeric carbonyl reductase that belongs to the SDR superfamily of proteins. It catalyzes the reduction of the lipid derived aldehyde 4-oxononenal. It contributes to protection against oxidative stress-induced neurodegeneration and prevention of apoptosis by removal of damaged cardiolipin; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.457 |
Mnn1 | sni | FBpp0110277 | FBpp0311239 | Menin 1 (Mnn1) encodes a protein that regulates the response of several stresses including hypoxia, hyperosmolarity, heat shock, and oxidative stress. It is important during the mitotic G1 DNA damage checkpoint in a process mediated by the product of CHES-1-like. | Sniffer, isoform A; Sniffer (sni) encodes a homodimeric carbonyl reductase that belongs to the SDR superfamily of proteins. It catalyzes the reduction of the lipid derived aldehyde 4-oxononenal. It contributes to protection against oxidative stress-induced neurodegeneration and prevention of apoptosis by removal of damaged cardiolipin; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.525 |
Sws1 | sni | FBpp0111424 | FBpp0311239 | SWIM domain containing Srs2 interacting protein 1 (Sws1) encodes a protein that is paralog-interacting of the product of spn-A. It is involved in homologous recombination in the repair of double-strand breaks, likely through the product of spn-A regulation. | Sniffer, isoform A; Sniffer (sni) encodes a homodimeric carbonyl reductase that belongs to the SDR superfamily of proteins. It catalyzes the reduction of the lipid derived aldehyde 4-oxononenal. It contributes to protection against oxidative stress-induced neurodegeneration and prevention of apoptosis by removal of damaged cardiolipin; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.668 |
Sws1 | sws | FBpp0111424 | FBpp0071077 | SWIM domain containing Srs2 interacting protein 1 (Sws1) encodes a protein that is paralog-interacting of the product of spn-A. It is involved in homologous recombination in the repair of double-strand breaks, likely through the product of spn-A regulation. | Neuropathy target esterase sws; Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy. Plays a role in the signaling mechanism between neurons and glia that regulates glia wrapping during development of the adult brain. Essential for membrane lipid homeostasis and cell survival in both neurons and glia of the adult brain; Belongs to the NTE family. | 0.790 |
Tmem18 | sni | FBpp0113013 | FBpp0311239 | Transmembrane protein 18. | Sniffer, isoform A; Sniffer (sni) encodes a homodimeric carbonyl reductase that belongs to the SDR superfamily of proteins. It catalyzes the reduction of the lipid derived aldehyde 4-oxononenal. It contributes to protection against oxidative stress-induced neurodegeneration and prevention of apoptosis by removal of damaged cardiolipin; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.531 |
Ugt37A3 | Cyp309a1 | FBpp0291574 | FBpp0307161 | UDP-glycosyltransferase family 37 member A3; Transferase activity, transferring hexosyl groups; UDP-glycosyltransferase activity. | Probable cytochrome P450 309a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | 0.699 |
Ugt37A3 | Cyp6d2 | FBpp0291574 | FBpp0071839 | UDP-glycosyltransferase family 37 member A3; Transferase activity, transferring hexosyl groups; UDP-glycosyltransferase activity. | Cyp6d2 (Cyp6d2) encodes a member of the cytochrome P450 oxidase protein family and is involved in the detoxification of toxic compounds. Two common Cyp6d2 alleles found in many Dmel stocks result in extreme sensitivity to camptothecin. | 0.635 |
Ugt37A3 | sni | FBpp0291574 | FBpp0311239 | UDP-glycosyltransferase family 37 member A3; Transferase activity, transferring hexosyl groups; UDP-glycosyltransferase activity. | Sniffer, isoform A; Sniffer (sni) encodes a homodimeric carbonyl reductase that belongs to the SDR superfamily of proteins. It catalyzes the reduction of the lipid derived aldehyde 4-oxononenal. It contributes to protection against oxidative stress-induced neurodegeneration and prevention of apoptosis by removal of damaged cardiolipin; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.497 |
Wwox | sni | FBpp0079172 | FBpp0311239 | WW domain containing oxidoreductase (Wwox) encodes a protein that contributes to homeostasis by regulating the balance between oxidative phosphorylation and glycolysis. It modulates the cell death mediated by the product of egr, which is accompanied by an increase in levels of reactive oxygen species; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Sniffer, isoform A; Sniffer (sni) encodes a homodimeric carbonyl reductase that belongs to the SDR superfamily of proteins. It catalyzes the reduction of the lipid derived aldehyde 4-oxononenal. It contributes to protection against oxidative stress-induced neurodegeneration and prevention of apoptosis by removal of damaged cardiolipin; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.435 |
sni | Cyp305a1 | FBpp0311239 | FBpp0074694 | Sniffer, isoform A; Sniffer (sni) encodes a homodimeric carbonyl reductase that belongs to the SDR superfamily of proteins. It catalyzes the reduction of the lipid derived aldehyde 4-oxononenal. It contributes to protection against oxidative stress-induced neurodegeneration and prevention of apoptosis by removal of damaged cardiolipin; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Probable cytochrome P450 305a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | 0.516 |
sni | Cyp309a1 | FBpp0311239 | FBpp0307161 | Sniffer, isoform A; Sniffer (sni) encodes a homodimeric carbonyl reductase that belongs to the SDR superfamily of proteins. It catalyzes the reduction of the lipid derived aldehyde 4-oxononenal. It contributes to protection against oxidative stress-induced neurodegeneration and prevention of apoptosis by removal of damaged cardiolipin; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Probable cytochrome P450 309a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | 0.451 |
sni | Cyp6d2 | FBpp0311239 | FBpp0071839 | Sniffer, isoform A; Sniffer (sni) encodes a homodimeric carbonyl reductase that belongs to the SDR superfamily of proteins. It catalyzes the reduction of the lipid derived aldehyde 4-oxononenal. It contributes to protection against oxidative stress-induced neurodegeneration and prevention of apoptosis by removal of damaged cardiolipin; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Cyp6d2 (Cyp6d2) encodes a member of the cytochrome P450 oxidase protein family and is involved in the detoxification of toxic compounds. Two common Cyp6d2 alleles found in many Dmel stocks result in extreme sensitivity to camptothecin. | 0.457 |
sni | Mnn1 | FBpp0311239 | FBpp0110277 | Sniffer, isoform A; Sniffer (sni) encodes a homodimeric carbonyl reductase that belongs to the SDR superfamily of proteins. It catalyzes the reduction of the lipid derived aldehyde 4-oxononenal. It contributes to protection against oxidative stress-induced neurodegeneration and prevention of apoptosis by removal of damaged cardiolipin; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Menin 1 (Mnn1) encodes a protein that regulates the response of several stresses including hypoxia, hyperosmolarity, heat shock, and oxidative stress. It is important during the mitotic G1 DNA damage checkpoint in a process mediated by the product of CHES-1-like. | 0.525 |
sni | Sws1 | FBpp0311239 | FBpp0111424 | Sniffer, isoform A; Sniffer (sni) encodes a homodimeric carbonyl reductase that belongs to the SDR superfamily of proteins. It catalyzes the reduction of the lipid derived aldehyde 4-oxononenal. It contributes to protection against oxidative stress-induced neurodegeneration and prevention of apoptosis by removal of damaged cardiolipin; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | SWIM domain containing Srs2 interacting protein 1 (Sws1) encodes a protein that is paralog-interacting of the product of spn-A. It is involved in homologous recombination in the repair of double-strand breaks, likely through the product of spn-A regulation. | 0.668 |
sni | Tmem18 | FBpp0311239 | FBpp0113013 | Sniffer, isoform A; Sniffer (sni) encodes a homodimeric carbonyl reductase that belongs to the SDR superfamily of proteins. It catalyzes the reduction of the lipid derived aldehyde 4-oxononenal. It contributes to protection against oxidative stress-induced neurodegeneration and prevention of apoptosis by removal of damaged cardiolipin; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Transmembrane protein 18. | 0.531 |
sni | Ugt37A3 | FBpp0311239 | FBpp0291574 | Sniffer, isoform A; Sniffer (sni) encodes a homodimeric carbonyl reductase that belongs to the SDR superfamily of proteins. It catalyzes the reduction of the lipid derived aldehyde 4-oxononenal. It contributes to protection against oxidative stress-induced neurodegeneration and prevention of apoptosis by removal of damaged cardiolipin; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | UDP-glycosyltransferase family 37 member A3; Transferase activity, transferring hexosyl groups; UDP-glycosyltransferase activity. | 0.497 |