STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG2263Phenylalanyl-tRNA synthetase, alpha-subunit is a cytoplasmic aminoacyl-tRNA synthetase that catalyzes the ligation of Phenylalanine to its cognate tRNAPhe. Together with the beta-subunit it forms a tetrameric enzyme complex. This subunit provides the catalytic core (498 aa)    
Predicted Functional Partners:
CG5706
Phenylalanyl-tRNA synthetase, beta-subunit is a cytoplasmic aminoacyl-tRNA synthetase that catalyzes the ligation of Phenylalanine to its cognate tRNAPhe. Together with the alpha-subunit it forms a tetrameric enzyme complex. This subunit plays a role in recognition and binding of tRNAPhe and it provides the editing site that hydrolyzes wrongfully activated or ligated compounds
  
 0.999
Aats-tyr
Tyrosine--tRNA ligase; tRNA binding; ATP binding; tyrosine-tRNA ligase activity. It is involved in the biological process described with: tyrosyl-tRNA aminoacylation
  
  
 0.991
CG5394
Bifunctional glutamate/proline--tRNA ligase; Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA; In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family
  
  
 0.984
Aats-asn
Asparaginyl-tRNA synthetase, isoform A; ATP binding; asparagine-tRNA ligase activity; nucleic acid binding. It is involved in the biological process described with: asparaginyl-tRNA aminoacylation
  
  
 0.963
Aats-lys
ATP binding; lysine-tRNA ligase activity; nucleic acid binding. It is involved in the biological process described with: lysyl-tRNA aminoacylation
  
  
 0.958
Aats-thr
Threonyl-tRNA synthetase, isoform A; threonine-tRNA ligase activity; ATP binding. It is involved in the biological process described with: threonyl-tRNA aminoacylation; neurogenesis
  
 
 0.944
Aats-his
Histidyl-tRNA synthetase, isoform D; ATP binding; histidine-tRNA ligase activity. It is involved in the biological process described with: histidyl-tRNA aminoacylation
  
 
 0.940
Aats-trp
Tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family
  
  
 0.911
Aats-phe
Probable phenylalanine--tRNA ligase, mitochondrial; Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation
   
 
0.903
mRpL39
39S ribosomal protein L39, mitochondrial; threonine-tRNA ligase activity; structural constituent of ribosome; nucleotide binding. It is involved in the biological process described with: threonyl-tRNA aminoacylation; translation; Belongs to the mitochondrion-specific ribosomal protein mL39 family
  
 
 0.893
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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