node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pxt | alphaTub67C | FBpp0082932 | FBpp0076122 | Chorion peroxidase; Peroxinectin-like (Pxt) encodes a cycloxygenase-like enzyme that contributes to the synthesis of prostaglandins. Prostaglandins activate G protein-coupled receptor signaling. Its roles include oogenesis, sperm individualization, morphogenesis, nucleolar structure, temporal control of gene expression, and regulation of gene amplification; Belongs to the peroxidase family. XPO subfamily. | Tubulin alpha-4 chain; alpha-Tubulin at 67C (alphaTub67C) encodes a protein that form heterodimers with beta-tubulins to polymerise and form microtubules. Tubulin molecules containing the product of alphaTub67C are essential for fast growth of the microtubules during the initial cleavage divisions of embryogenesis. | 0.853 |
Pxt | dhd | FBpp0082932 | FBpp0311766 | Chorion peroxidase; Peroxinectin-like (Pxt) encodes a cycloxygenase-like enzyme that contributes to the synthesis of prostaglandins. Prostaglandins activate G protein-coupled receptor signaling. Its roles include oogenesis, sperm individualization, morphogenesis, nucleolar structure, temporal control of gene expression, and regulation of gene amplification; Belongs to the peroxidase family. XPO subfamily. | Thioredoxin-1; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. As a reducing substrate of peroxiredoxin 1, thioredoxin 2 is preferred over thioredoxin 1. Required for female meiosis and early embryonic development. | 0.858 |
Pxt | fs(1)M3 | FBpp0082932 | FBpp0070857 | Chorion peroxidase; Peroxinectin-like (Pxt) encodes a cycloxygenase-like enzyme that contributes to the synthesis of prostaglandins. Prostaglandins activate G protein-coupled receptor signaling. Its roles include oogenesis, sperm individualization, morphogenesis, nucleolar structure, temporal control of gene expression, and regulation of gene amplification; Belongs to the peroxidase family. XPO subfamily. | Female sterile (1) M3 (fs(1)M3) encodes a protein that is required, along with the products of fs(1)N and clos, for their accumulation at the vitelline membrane and function in vitelline membrane integrity and Torso receptor activation. | 0.890 |
Pxt | gnu | FBpp0082932 | FBpp0075447 | Chorion peroxidase; Peroxinectin-like (Pxt) encodes a cycloxygenase-like enzyme that contributes to the synthesis of prostaglandins. Prostaglandins activate G protein-coupled receptor signaling. Its roles include oogenesis, sperm individualization, morphogenesis, nucleolar structure, temporal control of gene expression, and regulation of gene amplification; Belongs to the peroxidase family. XPO subfamily. | CG5272 protein; Giant nuclei (gnu) encodes a regulatory subunit of the PNG kinase complex, which regulates the levels of the protein encoded by CycB. Members of this complex are required maternally for the normal nuclear divisions of the syncytial embryo. | 0.844 |
Pxt | mtrm | FBpp0082932 | FBpp0076340 | Chorion peroxidase; Peroxinectin-like (Pxt) encodes a cycloxygenase-like enzyme that contributes to the synthesis of prostaglandins. Prostaglandins activate G protein-coupled receptor signaling. Its roles include oogenesis, sperm individualization, morphogenesis, nucleolar structure, temporal control of gene expression, and regulation of gene amplification; Belongs to the peroxidase family. XPO subfamily. | Protein matrimony; Polo kinase inhibitor required to maintain G2 arrest in the meiotic cell cycle in females. Holds heterochromatically paired homologs together from the end of pachytene until metaphase I. Haploinsufficient locus for homologous achiasmate segregation and may be required for the maintenance of heterochromatic pairings. | 0.855 |
Pxt | osk | FBpp0082932 | FBpp0081435 | Chorion peroxidase; Peroxinectin-like (Pxt) encodes a cycloxygenase-like enzyme that contributes to the synthesis of prostaglandins. Prostaglandins activate G protein-coupled receptor signaling. Its roles include oogenesis, sperm individualization, morphogenesis, nucleolar structure, temporal control of gene expression, and regulation of gene amplification; Belongs to the peroxidase family. XPO subfamily. | Maternal effect protein oskar; Organizes the germ plasm and directs localization of the posterior determinant nanos. Oskar protein is required to keep nos RNA and staufen protein at the posterior pole. | 0.985 |
Pxt | otu | FBpp0082932 | FBpp0089325 | Chorion peroxidase; Peroxinectin-like (Pxt) encodes a cycloxygenase-like enzyme that contributes to the synthesis of prostaglandins. Prostaglandins activate G protein-coupled receptor signaling. Its roles include oogenesis, sperm individualization, morphogenesis, nucleolar structure, temporal control of gene expression, and regulation of gene amplification; Belongs to the peroxidase family. XPO subfamily. | Protein ovarian tumor locus; Essential for female fertility; germ cell division and differentiation. | 0.848 |
Pxt | yl | FBpp0082932 | FBpp0073715 | Chorion peroxidase; Peroxinectin-like (Pxt) encodes a cycloxygenase-like enzyme that contributes to the synthesis of prostaglandins. Prostaglandins activate G protein-coupled receptor signaling. Its roles include oogenesis, sperm individualization, morphogenesis, nucleolar structure, temporal control of gene expression, and regulation of gene amplification; Belongs to the peroxidase family. XPO subfamily. | Putative vitellogenin receptor; Involved in uptake of vitellogenin by endocytosis. | 0.850 |
alphaTub67C | Pxt | FBpp0076122 | FBpp0082932 | Tubulin alpha-4 chain; alpha-Tubulin at 67C (alphaTub67C) encodes a protein that form heterodimers with beta-tubulins to polymerise and form microtubules. Tubulin molecules containing the product of alphaTub67C are essential for fast growth of the microtubules during the initial cleavage divisions of embryogenesis. | Chorion peroxidase; Peroxinectin-like (Pxt) encodes a cycloxygenase-like enzyme that contributes to the synthesis of prostaglandins. Prostaglandins activate G protein-coupled receptor signaling. Its roles include oogenesis, sperm individualization, morphogenesis, nucleolar structure, temporal control of gene expression, and regulation of gene amplification; Belongs to the peroxidase family. XPO subfamily. | 0.853 |
alphaTub67C | dhd | FBpp0076122 | FBpp0311766 | Tubulin alpha-4 chain; alpha-Tubulin at 67C (alphaTub67C) encodes a protein that form heterodimers with beta-tubulins to polymerise and form microtubules. Tubulin molecules containing the product of alphaTub67C are essential for fast growth of the microtubules during the initial cleavage divisions of embryogenesis. | Thioredoxin-1; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. As a reducing substrate of peroxiredoxin 1, thioredoxin 2 is preferred over thioredoxin 1. Required for female meiosis and early embryonic development. | 0.855 |
alphaTub67C | fs(1)M3 | FBpp0076122 | FBpp0070857 | Tubulin alpha-4 chain; alpha-Tubulin at 67C (alphaTub67C) encodes a protein that form heterodimers with beta-tubulins to polymerise and form microtubules. Tubulin molecules containing the product of alphaTub67C are essential for fast growth of the microtubules during the initial cleavage divisions of embryogenesis. | Female sterile (1) M3 (fs(1)M3) encodes a protein that is required, along with the products of fs(1)N and clos, for their accumulation at the vitelline membrane and function in vitelline membrane integrity and Torso receptor activation. | 0.791 |
alphaTub67C | gnu | FBpp0076122 | FBpp0075447 | Tubulin alpha-4 chain; alpha-Tubulin at 67C (alphaTub67C) encodes a protein that form heterodimers with beta-tubulins to polymerise and form microtubules. Tubulin molecules containing the product of alphaTub67C are essential for fast growth of the microtubules during the initial cleavage divisions of embryogenesis. | CG5272 protein; Giant nuclei (gnu) encodes a regulatory subunit of the PNG kinase complex, which regulates the levels of the protein encoded by CycB. Members of this complex are required maternally for the normal nuclear divisions of the syncytial embryo. | 0.848 |
alphaTub67C | mtrm | FBpp0076122 | FBpp0076340 | Tubulin alpha-4 chain; alpha-Tubulin at 67C (alphaTub67C) encodes a protein that form heterodimers with beta-tubulins to polymerise and form microtubules. Tubulin molecules containing the product of alphaTub67C are essential for fast growth of the microtubules during the initial cleavage divisions of embryogenesis. | Protein matrimony; Polo kinase inhibitor required to maintain G2 arrest in the meiotic cell cycle in females. Holds heterochromatically paired homologs together from the end of pachytene until metaphase I. Haploinsufficient locus for homologous achiasmate segregation and may be required for the maintenance of heterochromatic pairings. | 0.900 |
alphaTub67C | osk | FBpp0076122 | FBpp0081435 | Tubulin alpha-4 chain; alpha-Tubulin at 67C (alphaTub67C) encodes a protein that form heterodimers with beta-tubulins to polymerise and form microtubules. Tubulin molecules containing the product of alphaTub67C are essential for fast growth of the microtubules during the initial cleavage divisions of embryogenesis. | Maternal effect protein oskar; Organizes the germ plasm and directs localization of the posterior determinant nanos. Oskar protein is required to keep nos RNA and staufen protein at the posterior pole. | 0.897 |
alphaTub67C | otu | FBpp0076122 | FBpp0089325 | Tubulin alpha-4 chain; alpha-Tubulin at 67C (alphaTub67C) encodes a protein that form heterodimers with beta-tubulins to polymerise and form microtubules. Tubulin molecules containing the product of alphaTub67C are essential for fast growth of the microtubules during the initial cleavage divisions of embryogenesis. | Protein ovarian tumor locus; Essential for female fertility; germ cell division and differentiation. | 0.880 |
alphaTub67C | yl | FBpp0076122 | FBpp0073715 | Tubulin alpha-4 chain; alpha-Tubulin at 67C (alphaTub67C) encodes a protein that form heterodimers with beta-tubulins to polymerise and form microtubules. Tubulin molecules containing the product of alphaTub67C are essential for fast growth of the microtubules during the initial cleavage divisions of embryogenesis. | Putative vitellogenin receptor; Involved in uptake of vitellogenin by endocytosis. | 0.855 |
bam | otu | FBpp0084243 | FBpp0089325 | Bag of marbles (bam) encodes a protein involved in gametogenesis that is associated with the fusome, a germ cell-specific organelle. It contributes to the fate determination of germline stem cells, in which bam is negatively regulated by the BMP signaling pathway. | Protein ovarian tumor locus; Essential for female fertility; germ cell division and differentiation. | 0.874 |
dhd | Pxt | FBpp0311766 | FBpp0082932 | Thioredoxin-1; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. As a reducing substrate of peroxiredoxin 1, thioredoxin 2 is preferred over thioredoxin 1. Required for female meiosis and early embryonic development. | Chorion peroxidase; Peroxinectin-like (Pxt) encodes a cycloxygenase-like enzyme that contributes to the synthesis of prostaglandins. Prostaglandins activate G protein-coupled receptor signaling. Its roles include oogenesis, sperm individualization, morphogenesis, nucleolar structure, temporal control of gene expression, and regulation of gene amplification; Belongs to the peroxidase family. XPO subfamily. | 0.858 |
dhd | alphaTub67C | FBpp0311766 | FBpp0076122 | Thioredoxin-1; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. As a reducing substrate of peroxiredoxin 1, thioredoxin 2 is preferred over thioredoxin 1. Required for female meiosis and early embryonic development. | Tubulin alpha-4 chain; alpha-Tubulin at 67C (alphaTub67C) encodes a protein that form heterodimers with beta-tubulins to polymerise and form microtubules. Tubulin molecules containing the product of alphaTub67C are essential for fast growth of the microtubules during the initial cleavage divisions of embryogenesis. | 0.855 |
dhd | fs(1)M3 | FBpp0311766 | FBpp0070857 | Thioredoxin-1; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. As a reducing substrate of peroxiredoxin 1, thioredoxin 2 is preferred over thioredoxin 1. Required for female meiosis and early embryonic development. | Female sterile (1) M3 (fs(1)M3) encodes a protein that is required, along with the products of fs(1)N and clos, for their accumulation at the vitelline membrane and function in vitelline membrane integrity and Torso receptor activation. | 0.457 |