node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Atu | CG3909 | FBpp0078353 | FBpp0081650 | Another transcription unit protein; RNA polymerase II C-terminal domain phosphoserine binding. It is involved in the biological process described with: positive regulation of transcription elongation from RNA polymerase II promoter; histone modification; regulation of hemocyte proliferation. | WD_REPEATS_REGION domain-containing protein. | 0.903 |
Atu | CG6220 | FBpp0078353 | FBpp0086776 | Another transcription unit protein; RNA polymerase II C-terminal domain phosphoserine binding. It is involved in the biological process described with: positive regulation of transcription elongation from RNA polymerase II promoter; histone modification; regulation of hemocyte proliferation. | FI06213p; RNA polymerase II complex binding. It is involved in the biological process described with: positive regulation of transcription elongation from RNA polymerase II promoter; recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex; histone modification; negative regulation of transcription by RNA polymerase II. | 0.892 |
Atu | CG9899 | FBpp0078353 | FBpp0071879 | Another transcription unit protein; RNA polymerase II C-terminal domain phosphoserine binding. It is involved in the biological process described with: positive regulation of transcription elongation from RNA polymerase II promoter; histone modification; regulation of hemocyte proliferation. | TPR_REGION domain-containing protein; RNA polymerase II complex binding; SH2 domain binding. It is involved in the biological process described with: positive regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated; regulation of histone H3-K4 methylation. | 0.988 |
Atu | Spt5 | FBpp0078353 | FBpp0085716 | Another transcription unit protein; RNA polymerase II C-terminal domain phosphoserine binding. It is involved in the biological process described with: positive regulation of transcription elongation from RNA polymerase II promoter; histone modification; regulation of hemocyte proliferation. | Transcription elongation factor SPT5; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II. DSIF enhances transcriptional pausing at sites proximal to the promoter, which may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF may also promote transcriptional elongation within coding regions. DSIF is required for the transcriptional induction of heat shock response genes and regulation of genes which control anterior-posterior patterning during embryonic development; Belongs [...] | 0.946 |
Atu | Spt6 | FBpp0078353 | FBpp0070861 | Another transcription unit protein; RNA polymerase II C-terminal domain phosphoserine binding. It is involved in the biological process described with: positive regulation of transcription elongation from RNA polymerase II promoter; histone modification; regulation of hemocyte proliferation. | Transcription elongation factor SPT6; Transcription elongation factor which binds histone H3 and enhances transcription elongation by RNA polymerase II (RNAPII). Required for the transcriptional induction of heat shock response genes and for maximal recruitment of two other elongation factors, Spt5 and Paf1, to the induced Hsp70. Plays a critical role in normal fly development throughout the lifecycle. | 0.918 |
Atu | Ssrp | FBpp0078353 | FBpp0072151 | Another transcription unit protein; RNA polymerase II C-terminal domain phosphoserine binding. It is involved in the biological process described with: positive regulation of transcription elongation from RNA polymerase II promoter; histone modification; regulation of hemocyte proliferation. | FACT complex subunit Ssrp1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] | 0.949 |
Atu | atms | FBpp0078353 | FBpp0306920 | Another transcription unit protein; RNA polymerase II C-terminal domain phosphoserine binding. It is involved in the biological process described with: positive regulation of transcription elongation from RNA polymerase II promoter; histone modification; regulation of hemocyte proliferation. | Antimeros, isoform A; Antimeros (atms) encodes a component of the PAF1 complex (together with the products of Atu, hyx, Rtf1 and Ctr9). The PAF1 complex physically interacts with components of the basal transcription machinery and sequence-specific transcription factors to control histone modifications and pause release. | 0.995 |
Atu | dre4 | FBpp0078353 | FBpp0072743 | Another transcription unit protein; RNA polymerase II C-terminal domain phosphoserine binding. It is involved in the biological process described with: positive regulation of transcription elongation from RNA polymerase II promoter; histone modification; regulation of hemocyte proliferation. | FACT complex subunit spt16; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] | 0.964 |
Atu | hyx | FBpp0078353 | FBpp0289644 | Another transcription unit protein; RNA polymerase II C-terminal domain phosphoserine binding. It is involved in the biological process described with: positive regulation of transcription elongation from RNA polymerase II promoter; histone modification; regulation of hemocyte proliferation. | Hyrax, isoform A; Hyrax (hyx) encodes a protein recruited by signaling pathway specific transcriptional regulators such as the products of arm and ci and is important for the output of Wingless and Hedgehog pathways. | 0.982 |
Atu | spt4 | FBpp0078353 | FBpp0086953 | Another transcription unit protein; RNA polymerase II C-terminal domain phosphoserine binding. It is involved in the biological process described with: positive regulation of transcription elongation from RNA polymerase II promoter; histone modification; regulation of hemocyte proliferation. | Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II. DSIF enhances transcriptional pausing at sites proximal to the promoter, which may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF may also promote transcriptional elongation within coding regions. DSIF is required for the transcriptional induction of heat shock response genes and regulation of genes which control anterior-posterior patterning during embryonic development (By simi [...] | 0.926 |
CG3909 | Atu | FBpp0081650 | FBpp0078353 | WD_REPEATS_REGION domain-containing protein. | Another transcription unit protein; RNA polymerase II C-terminal domain phosphoserine binding. It is involved in the biological process described with: positive regulation of transcription elongation from RNA polymerase II promoter; histone modification; regulation of hemocyte proliferation. | 0.903 |
CG3909 | CG6220 | FBpp0081650 | FBpp0086776 | WD_REPEATS_REGION domain-containing protein. | FI06213p; RNA polymerase II complex binding. It is involved in the biological process described with: positive regulation of transcription elongation from RNA polymerase II promoter; recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex; histone modification; negative regulation of transcription by RNA polymerase II. | 0.979 |
CG3909 | CG9899 | FBpp0081650 | FBpp0071879 | WD_REPEATS_REGION domain-containing protein. | TPR_REGION domain-containing protein; RNA polymerase II complex binding; SH2 domain binding. It is involved in the biological process described with: positive regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated; regulation of histone H3-K4 methylation. | 0.970 |
CG3909 | Spt5 | FBpp0081650 | FBpp0085716 | WD_REPEATS_REGION domain-containing protein. | Transcription elongation factor SPT5; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II. DSIF enhances transcriptional pausing at sites proximal to the promoter, which may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF may also promote transcriptional elongation within coding regions. DSIF is required for the transcriptional induction of heat shock response genes and regulation of genes which control anterior-posterior patterning during embryonic development; Belongs [...] | 0.956 |
CG3909 | Spt6 | FBpp0081650 | FBpp0070861 | WD_REPEATS_REGION domain-containing protein. | Transcription elongation factor SPT6; Transcription elongation factor which binds histone H3 and enhances transcription elongation by RNA polymerase II (RNAPII). Required for the transcriptional induction of heat shock response genes and for maximal recruitment of two other elongation factors, Spt5 and Paf1, to the induced Hsp70. Plays a critical role in normal fly development throughout the lifecycle. | 0.845 |
CG3909 | Ssrp | FBpp0081650 | FBpp0072151 | WD_REPEATS_REGION domain-containing protein. | FACT complex subunit Ssrp1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] | 0.660 |
CG3909 | atms | FBpp0081650 | FBpp0306920 | WD_REPEATS_REGION domain-containing protein. | Antimeros, isoform A; Antimeros (atms) encodes a component of the PAF1 complex (together with the products of Atu, hyx, Rtf1 and Ctr9). The PAF1 complex physically interacts with components of the basal transcription machinery and sequence-specific transcription factors to control histone modifications and pause release. | 0.994 |
CG3909 | dre4 | FBpp0081650 | FBpp0072743 | WD_REPEATS_REGION domain-containing protein. | FACT complex subunit spt16; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] | 0.704 |
CG3909 | hyx | FBpp0081650 | FBpp0289644 | WD_REPEATS_REGION domain-containing protein. | Hyrax, isoform A; Hyrax (hyx) encodes a protein recruited by signaling pathway specific transcriptional regulators such as the products of arm and ci and is important for the output of Wingless and Hedgehog pathways. | 0.999 |
CG3909 | spt4 | FBpp0081650 | FBpp0086953 | WD_REPEATS_REGION domain-containing protein. | Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II. DSIF enhances transcriptional pausing at sites proximal to the promoter, which may facilitate the assembly of an elongation competent RNA polymerase II complex. DSIF may also promote transcriptional elongation within coding regions. DSIF is required for the transcriptional induction of heat shock response genes and regulation of genes which control anterior-posterior patterning during embryonic development (By simi [...] | 0.863 |