node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG2199 | CG8924 | FBpp0072605 | FBpp0073935 | Zinc finger protein CG2199; May be involved in transcriptional regulation. | LD19131p; DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | 0.691 |
CG2199 | mri | FBpp0072605 | FBpp0072383 | Zinc finger protein CG2199; May be involved in transcriptional regulation. | Mrityu, isoform A; Mrityu (mri) encodes a BTB/POZ domain containing protein. Its expression is regulated by the product of klu during retinal apoptosis. mri protein is phosphorylated upon egg activation, and is required for early embryo development and for the normal sensory perception of touch. | 0.680 |
CG2199 | pita | FBpp0072605 | FBpp0072021 | Zinc finger protein CG2199; May be involved in transcriptional regulation. | Pita, isoform A; Pita (pita) encodes an architectural chromatin protein essential for embryonic development that organizes open chromatin in the regulatory regions (predominantly promoters). pita product functions include enhancer blocking, support of distant interactions, protection from spreading of repressed chromatin and recruitment of transcription factors. | 0.683 |
CG5003 | CG7154 | FBpp0084641 | FBpp0079111 | FI05230p; It is involved in the biological process described with: regulation of cell cycle; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; G2/M transition of mitotic cell cycle. | LD22651p; Lysine-acetylated histone binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | 0.720 |
CG5003 | Topors | FBpp0084641 | FBpp0304302 | FI05230p; It is involved in the biological process described with: regulation of cell cycle; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; G2/M transition of mitotic cell cycle. | E3 ubiquitin-protein ligase Topors; Functions as a ubiquitin-protein E3 ligase. Negatively regulates the transcriptional repressor h/hairy by promoting its ubiquitination and subsequent degradation. Also directs the nuclear organization of the gypsy chromatin insulator. Chromatin insulators are regulatory elements which establish independent domains of transcriptional activity within eukaryotic genomes. Insulators have two defining properties; they can block the communication between an enhancer and a promoter when placed between them, and can also buffer transgenes from position effec [...] | 0.448 |
CG5003 | pita | FBpp0084641 | FBpp0072021 | FI05230p; It is involved in the biological process described with: regulation of cell cycle; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; G2/M transition of mitotic cell cycle. | Pita, isoform A; Pita (pita) encodes an architectural chromatin protein essential for embryonic development that organizes open chromatin in the regulatory regions (predominantly promoters). pita product functions include enhancer blocking, support of distant interactions, protection from spreading of repressed chromatin and recruitment of transcription factors. | 0.579 |
CG7154 | CG5003 | FBpp0079111 | FBpp0084641 | LD22651p; Lysine-acetylated histone binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | FI05230p; It is involved in the biological process described with: regulation of cell cycle; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; G2/M transition of mitotic cell cycle. | 0.720 |
CG7154 | Topors | FBpp0079111 | FBpp0304302 | LD22651p; Lysine-acetylated histone binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | E3 ubiquitin-protein ligase Topors; Functions as a ubiquitin-protein E3 ligase. Negatively regulates the transcriptional repressor h/hairy by promoting its ubiquitination and subsequent degradation. Also directs the nuclear organization of the gypsy chromatin insulator. Chromatin insulators are regulatory elements which establish independent domains of transcriptional activity within eukaryotic genomes. Insulators have two defining properties; they can block the communication between an enhancer and a promoter when placed between them, and can also buffer transgenes from position effec [...] | 0.505 |
CG7154 | pita | FBpp0079111 | FBpp0072021 | LD22651p; Lysine-acetylated histone binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | Pita, isoform A; Pita (pita) encodes an architectural chromatin protein essential for embryonic development that organizes open chromatin in the regulatory regions (predominantly promoters). pita product functions include enhancer blocking, support of distant interactions, protection from spreading of repressed chromatin and recruitment of transcription factors. | 0.544 |
CG8924 | CG2199 | FBpp0073935 | FBpp0072605 | LD19131p; DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | Zinc finger protein CG2199; May be involved in transcriptional regulation. | 0.691 |
CG8924 | mri | FBpp0073935 | FBpp0072383 | LD19131p; DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | Mrityu, isoform A; Mrityu (mri) encodes a BTB/POZ domain containing protein. Its expression is regulated by the product of klu during retinal apoptosis. mri protein is phosphorylated upon egg activation, and is required for early embryo development and for the normal sensory perception of touch. | 0.603 |
CG8924 | pita | FBpp0073935 | FBpp0072021 | LD19131p; DNA binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II. | Pita, isoform A; Pita (pita) encodes an architectural chromatin protein essential for embryonic development that organizes open chromatin in the regulatory regions (predominantly promoters). pita product functions include enhancer blocking, support of distant interactions, protection from spreading of repressed chromatin and recruitment of transcription factors. | 0.635 |
Cp190 | Ibf2 | FBpp0082581 | FBpp0081464 | Centrosome-associated zinc finger protein CP190; Component of the gypsy chromatin insulator complex which is required for the function of the gypsy chromatin insulator and other endogenous chromatin insulators. Chromatin insulators are regulatory elements which establish independent domains of transcriptional activity within eukaryotic genomes. Insulators have two defining properties; they can block the communication between an enhancer and a promoter when placed between them and can also buffer transgenes from position effect variegation (PEV). Insulators are proposed to structure the [...] | Insulator binding factor 2; Protein binding; sequence-specific DNA binding; chromatin insulator sequence binding. It is involved in the biological process described with: positive regulation of chromatin silencing; regulation of gene expression. | 0.947 |
Cp190 | Topors | FBpp0082581 | FBpp0304302 | Centrosome-associated zinc finger protein CP190; Component of the gypsy chromatin insulator complex which is required for the function of the gypsy chromatin insulator and other endogenous chromatin insulators. Chromatin insulators are regulatory elements which establish independent domains of transcriptional activity within eukaryotic genomes. Insulators have two defining properties; they can block the communication between an enhancer and a promoter when placed between them and can also buffer transgenes from position effect variegation (PEV). Insulators are proposed to structure the [...] | E3 ubiquitin-protein ligase Topors; Functions as a ubiquitin-protein E3 ligase. Negatively regulates the transcriptional repressor h/hairy by promoting its ubiquitination and subsequent degradation. Also directs the nuclear organization of the gypsy chromatin insulator. Chromatin insulators are regulatory elements which establish independent domains of transcriptional activity within eukaryotic genomes. Insulators have two defining properties; they can block the communication between an enhancer and a promoter when placed between them, and can also buffer transgenes from position effec [...] | 0.819 |
Cp190 | ZIPIC | FBpp0082581 | FBpp0084965 | Centrosome-associated zinc finger protein CP190; Component of the gypsy chromatin insulator complex which is required for the function of the gypsy chromatin insulator and other endogenous chromatin insulators. Chromatin insulators are regulatory elements which establish independent domains of transcriptional activity within eukaryotic genomes. Insulators have two defining properties; they can block the communication between an enhancer and a promoter when placed between them and can also buffer transgenes from position effect variegation (PEV). Insulators are proposed to structure the [...] | Zinc-finger protein interacting with CP190 (ZIPIC) encodes a promoter-binding transcription factor that displays architectural and insulator functions. | 0.926 |
Cp190 | pita | FBpp0082581 | FBpp0072021 | Centrosome-associated zinc finger protein CP190; Component of the gypsy chromatin insulator complex which is required for the function of the gypsy chromatin insulator and other endogenous chromatin insulators. Chromatin insulators are regulatory elements which establish independent domains of transcriptional activity within eukaryotic genomes. Insulators have two defining properties; they can block the communication between an enhancer and a promoter when placed between them and can also buffer transgenes from position effect variegation (PEV). Insulators are proposed to structure the [...] | Pita, isoform A; Pita (pita) encodes an architectural chromatin protein essential for embryonic development that organizes open chromatin in the regulatory regions (predominantly promoters). pita product functions include enhancer blocking, support of distant interactions, protection from spreading of repressed chromatin and recruitment of transcription factors. | 0.647 |
Ibf2 | Cp190 | FBpp0081464 | FBpp0082581 | Insulator binding factor 2; Protein binding; sequence-specific DNA binding; chromatin insulator sequence binding. It is involved in the biological process described with: positive regulation of chromatin silencing; regulation of gene expression. | Centrosome-associated zinc finger protein CP190; Component of the gypsy chromatin insulator complex which is required for the function of the gypsy chromatin insulator and other endogenous chromatin insulators. Chromatin insulators are regulatory elements which establish independent domains of transcriptional activity within eukaryotic genomes. Insulators have two defining properties; they can block the communication between an enhancer and a promoter when placed between them and can also buffer transgenes from position effect variegation (PEV). Insulators are proposed to structure the [...] | 0.947 |
Ibf2 | ZIPIC | FBpp0081464 | FBpp0084965 | Insulator binding factor 2; Protein binding; sequence-specific DNA binding; chromatin insulator sequence binding. It is involved in the biological process described with: positive regulation of chromatin silencing; regulation of gene expression. | Zinc-finger protein interacting with CP190 (ZIPIC) encodes a promoter-binding transcription factor that displays architectural and insulator functions. | 0.935 |
Ibf2 | pita | FBpp0081464 | FBpp0072021 | Insulator binding factor 2; Protein binding; sequence-specific DNA binding; chromatin insulator sequence binding. It is involved in the biological process described with: positive regulation of chromatin silencing; regulation of gene expression. | Pita, isoform A; Pita (pita) encodes an architectural chromatin protein essential for embryonic development that organizes open chromatin in the regulatory regions (predominantly promoters). pita product functions include enhancer blocking, support of distant interactions, protection from spreading of repressed chromatin and recruitment of transcription factors. | 0.516 |
Myb | pita | FBpp0089405 | FBpp0072021 | Myb protein; DNA-binding protein that specifically recognizes the sequence 5'-YAAC[GT]G-3'. Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. In follicle cells, the complex plays a central role in the site-specific DNA replication at the chorion loci. During development, the complex represses transcription of developmentally controlled E2F target genes. | Pita, isoform A; Pita (pita) encodes an architectural chromatin protein essential for embryonic development that organizes open chromatin in the regulatory regions (predominantly promoters). pita product functions include enhancer blocking, support of distant interactions, protection from spreading of repressed chromatin and recruitment of transcription factors. | 0.618 |