STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG17658FI21801p1. (478 aa)    
Predicted Functional Partners:
CG7271
RE03769p; Nucleic acid binding.
      
 0.792
CG14545
RE55691p.
   
  
 0.731
CG4281
GH10944p.
      
 0.680
sov
Small ovary, isoform A; Nucleic acid binding.
   
 
 0.677
CG14838
Uncharacterized protein; Dynein heavy chain binding; dynein light chain binding. It is involved in the biological process described with: microtubule-based movement; outer dynein arm assembly; cilium movement.
      
 0.671
TMEM216
Transmembrane protein 216, isoform A; It is involved in the biological process described with: non-motile cilium assembly; cilium assembly.
   
  
 0.628
Bsg25D
Blastoderm-specific gene 25D (Bsg25D) encodes the ortholog of Ninein, a microtubule-anchoring protein in humans. Bsg25D is highly expressed at blastoderm stage embryos and its product localizes to the centrosome periphery.
      
 0.607
zpg
Innexin inx4; Structural component of the gap junctions in germline cells. Required for differentiation and survival of germline cysts in females and of spermatogonia in males; gap junctional communication between spermatogonia and somatic cyst cells may be required for normal differentiation and survival of spermatogonia. Belongs to the pannexin family.
   
 
 0.572
pgc
Polar granule component (pgc) encodes a small polypeptide involved in transcriptional silencing in primordial germ cells and in germ cell specification. It interacts with the RpII215/Spn43Ab complex that regulates RNA polymerase II expression.
   
  
 0.552
Pfas
Phosphoribosylformylglycinamidine synthase (Pfas) encodes a phosphoribosylformylglycinamidine synthase, which is an essential enzyme in the pathway for de novo synthesis of the purine nucleotide inosine monophosphate (IMP). IMP is the precursor for purine nucleotides required for nucleic acids, energy transfer, cell signaling, and coenzymes; In the N-terminal section; belongs to the FGAMS family.
   
  
 0.496
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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