STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gammaSnap1Gamma Soluble NSF attachment protein 1 (gammaSnap1) encodes a protein involved in the dorsal/ventral pattern formation of the wing disc. (302 aa)    
Predicted Functional Partners:
alphaSnap
Alpha-soluble NSF attachment protein; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. Also between the endosome and phagosome.
   
 0.987
Nsf2
Vesicle-fusing ATPase 2; Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin (By similarity).
   
 0.909
Syx8
Syntaxin 8; SNAP receptor activity; SNARE binding. It is involved in the biological process described with: intracellular protein transport; synaptic vesicle docking; vesicle fusion; vesicle docking.
   
 0.897
Gos28
Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor (By similarity).
   
 0.883
Snap29
Synaptosomal-associated protein 29kDa (Snap29) encodes a member of the SNARE (soluble N-ethylmaleimide-sensitive factor-attachment protein (SNAP) receptor) family. It is involved in regulation of autophagy, endocytic recycling and cell division.
   
 0.880
Vti1a
Vesicle transport through interaction with t-SNAREs 1a (Vti1a) encodes a protein involved in vesicle trafficking.
   
 0.877
Syx6
Syntaxin 6, isoform E; SNARE binding; SNAP receptor activity.
 
  
 0.855
Syx16
Syntaxin 16 (Syx16) encodes a member of the soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE) family. It is localized to late Golgi compartments and is part of a trans-SNARE complex responsible for endosome-to-Golgi/trans Golgi network retrograde transport.
   
 0.853
Syx13
Syntaxin 13 (Syx13) encodes a member of the syntaxin family of t-SNAREs that mediate vesicle fusion within cells. It localizes to endosomes and is involved in autophagosome maturation.
   
 0.852
Syx5
Syntaxin-5; Syntaxin 5 (Syx5) encodes a type II transmembrane protein in the Q-SNARE family that forms hetero tetramers required for membrane function in the early secretory pathway (ER and Golgi). It has been involved in cytokinesis during spermatogenesis.
    
 0.839
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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