STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (245 aa)    
Predicted Functional Partners:
RpL31
60S ribosomal protein L31; Structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; Belongs to the eukaryotic ribosomal protein eL31 family.
  
 
 0.998
RpL18A
60S ribosomal protein L18a; Structural constituent of ribosome. It is involved in the biological process described with: translation; cytoplasmic translation; Belongs to the eukaryotic ribosomal protein eL20 family.
  
 
 0.997
RpL30
Ribosomal protein L30, isoform B; RNA binding; structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; translation.
   
 
 0.997
RpL23
60S ribosomal protein L23; Large ribosomal subunit rRNA binding; structural constituent of ribosome; myosin binding. It is involved in the biological process described with: translation; cytoplasmic translation; Belongs to the universal ribosomal protein uL14 family.
  
 
 0.995
RpL3
60S ribosomal protein L3; The L3 protein is a component of the large subunit of cytoplasmic ribosomes.
  
 
 0.994
RpL24-like
Probable ribosome biogenesis protein RLP24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of NOG1 to pre-60S particles (By similarity).
   
 
 0.993
Non1
Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit (By similarity). Required for normal assembly of the mitotic spindle. May be involved in both centrosome-dependent and centrosome-independent spindle assembly programs. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
   
 
 0.993
RpL5
60S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]
  
 
 0.993
RpLP0-like
Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
  
 0.992
RpL10
60S ribosomal protein L10; Structural constituent of ribosome. It is involved in the biological process described with: translation; ribosomal large subunit assembly; cytoplasmic translation.
   
 
 0.992
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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