STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lcp9Larval cuticle protein 9; Component of the cuticle of the larva. (92 aa)    
Predicted Functional Partners:
Lcp2
Larval cuticle protein 2; Component of the larval cuticle.
   
    0.808
CG14258
Uncharacterized protein.
   
    0.750
Lcp3
Larval cuticle protein 3; Component of the larval cuticle.
   
    0.738
GMF
Glia maturation factor (GMF) encodes a protein belonging to the ADF-H domain family of proteins, which promote dissambly of actin networks. It specifically binds to and promotes disassembly of Arp2/3-nucleated lamellipodial actin networks. It plays a role in promoting protrusion dynamics during cell migration.
      
 0.735
CG11349
MIP31077p.
   
   0.722
shrb
GH13992p; Shrub (shrb) encodes Shrub encodes Vps32/Snf7, a filament-forming subunit of the ESCRT-III complex involved in inward membrane budding. It regulates multiple cellular processes involving ESCRTs activity including multivesicular body biogenesis, cytokinesis, membrane repair and regulation of membrane associated signaling.
   
 
 0.711
Lcp65Ab2
Larval cuticle protein 65Ab1; Component of the cuticle of the larva.
      
 0.672
yellow-h
Yellow-h.
      
 0.671
mthl10
Probable G-protein coupled receptor Mth-like 10; G protein-coupled receptor activity. It is involved in the biological process described with: determination of adult lifespan; response to starvation; G protein-coupled receptor signaling pathway; cell surface receptor signaling pathway; Belongs to the G-protein coupled receptor 2 family. Mth subfamily.
    
 
 0.670
Lcp4
Larval cuticle protein 4; Component of the larval cuticle.
   
    0.657
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.