STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Vti1aVesicle transport through interaction with t-SNAREs 1a (Vti1a) encodes a protein involved in vesicle trafficking. (230 aa)    
Predicted Functional Partners:
Ykt6
YKT6 v-SNARE; Protein-cysteine S-palmitoyltransferase activity; SNAP receptor activity. It is involved in the biological process described with: endoplasmic reticulum to Golgi vesicle-mediated transport; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; vesicle-mediated transport; Belongs to the synaptobrevin family.
   
 0.999
alphaSnap
Alpha-soluble NSF attachment protein; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. Also between the endosome and phagosome.
   
 0.999
Syx16
Syntaxin 16 (Syx16) encodes a member of the soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE) family. It is localized to late Golgi compartments and is part of a trans-SNARE complex responsible for endosome-to-Golgi/trans Golgi network retrograde transport.
   
 0.999
Syx5
Syntaxin-5; Syntaxin 5 (Syx5) encodes a type II transmembrane protein in the Q-SNARE family that forms hetero tetramers required for membrane function in the early secretory pathway (ER and Golgi). It has been involved in cytokinesis during spermatogenesis.
   
 0.999
Syx6
Syntaxin 6, isoform E; SNARE binding; SNAP receptor activity.
   
 0.999
Syx8
Syntaxin 8; SNAP receptor activity; SNARE binding. It is involved in the biological process described with: intracellular protein transport; synaptic vesicle docking; vesicle fusion; vesicle docking.
   
 0.998
Sec22
Secretory 22, isoform B; Secretory 22 (Sec22) encodes a protein involved in Wnt protein secretion; Belongs to the synaptobrevin family.
   
 0.998
Syx7
Syntaxin 7 (Syx7) encodes a SNARE protein that is part of the core machinery (including the products of Rab5, Rbsn-5, and Vps45) by which endocytic cargo vesicles fuse with the early endosome.
   
 0.997
Vamp7
Vesicle-associated membrane protein 7 (Vamp7) encodes an R type SNARE protein. It mediates the fusion of autophagosomes with endosomes and lysosomes by forming a SNARE complex with the products of Syx17 and Snap29. It localizes to endosomes in a Rab21 and Sbf dependent manner; Belongs to the synaptobrevin family.
   
 0.996
Bet1
Blocked early in transport 1, isoform A; SNAP receptor activity; syntaxin binding. It is involved in the biological process described with: vesicle fusion with Golgi apparatus; vesicle-mediated transport; protein transport; endoplasmic reticulum to Golgi vesicle-mediated transport.
    
 0.986
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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