Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Open rectifier potassium channel activity (729 aa)
Predicted Functional Partners:
Receptor signaling protein serine/threonine kinase activity (577 aa)
Zinc ion binding; nucleic acid binding (525 aa)
RE60616p (714 aa)
Zinc ion binding; nucleic acid binding (412 aa)
Paralytic; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient (2145 aa)
Na channel protein 60E; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Plays a role in processing of olfactory information during the olfactory avoidance response (2896 aa)
Narrow abdomen (2232 aa)
Voltage-gated calcium channel activity; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. Encodes a dihydropyridine- and diltiazem-sensitive current in larval body wall muscle. Vital for embryonic development (2552 aa)
CG7530, isoform A (351 aa)
RNA binding; DNA binding (510 aa)
Your Current Organism:
NCBI taxonomy Id: 7227 Other names: D. melanogaster, Drosophila melanogaster, fruit fly