STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG2199Zinc finger protein CG2199; May be involved in transcriptional regulation (733 aa)    
Predicted Functional Partners:
CG11583
Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit
   
    0.800
CG41099
Uncharacterized protein, isoform C; Metal ion binding. It is involved in the biological process described with: epithelial cell morphogenesis; embryonic morphogenesis; endocytosis
   
 
 0.754
Rbp1
RNA-binding protein 1; Contributes to the activation of female-specific DSX splicing in vivo by recognizing the RBP1 target sequences within the purine-rich polypyrimidine tract of the female-specific 3' splice site; Belongs to the splicing factor SR family
    
   0.709
row
Relative of woc, isoform A; DNA binding; protein binding; metal ion binding; chromatin binding. It is involved in the biological process described with: regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-templated
   
  
 0.680
Sry-delta
Serendipity locus protein delta; Transcriptional activator that controls bicoid gene expression during oogenesis. Found in transcriptionally active cells. Binds to specific sites on polytene chromosomes of third instar larvae. Binds to the consensus DNA sequence 5'- YTAGAGATGGRAA-3'
   
  
 0.676
CG8924
LD19131p; DNA binding
   
  
 0.641
pita
Pita, isoform A; DNA binding; zinc ion binding. It is involved in the biological process described with: regulation of gene silencing; mitotic nuclear division; DNA endoreduplication; DNA replication
   
  
 0.618
mod
DNA-binding protein modulo; Its capacity to bind DNA and protein(s), and its differential expression during development suggest a role in the regulation of gene expression during Drosophila development. It could, in interaction with other factors, be required for the translation of instructions provided by pattern forming genes and controls, via chromatin changes, the activity of genes critical for the process of morphogenesis of several embryonic territories
   
    0.597
l(3)neo38
Lethal (3) neo38, isoform B; Sequence-specific DNA binding transcription factor activity; metal ion binding; nucleic acid binding. It is involved in the biological process described with: regulation of chromatin silencing; imaginal disc-derived wing morphogenesis
      
 0.590
Ote
Otefin; Inner nuclear membrane protein. Involved in the attachment of membrane vesicles to chromatin during nuclear assembly, and is probably required for centrosome maturation and cell cycle progression during mitosis. Essential for differentiation of certain tissues and the maintenance of progenitor cell populations. Required for the differentiation and maintenance of male and female germline stem cells (GSCs), as well as the maintenance of somatic cells in the GSC niche. This role is likely to be independent of the BMP (Dpp) pathway that negatively regulates bam transcription during [...]
   
   0.555
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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