node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Klp61F | Klp67A | FBpp0072616 | FBpp0312148 | Kinesin-like protein Klp61F; Important role in mitotic dividing cells. Microtubule motor required for spindle body separation. Slow plus-end directed microtubule motor capable of cross-linking and sliding apart antiparallel microtubules, thereby pushing apart the associated spindle poles during spindle assembly and function. Forms cross-links between microtubules within interpolar microtubule bundles. Contributes to the length of the metaphase spindle, maintains the prometaphase spindle by antagonizing Ncd, drives anaphase B, and also contributes to normal chromosome congression, kinet [...] | Kinesin-like protein at 67A (Klp67A) encodes a microtubule motor protein involved in chromosome congression and mitotic spindle morphogenesis; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.994 |
Klp61F | SMC2 | FBpp0072616 | FBpp0086591 | Kinesin-like protein Klp61F; Important role in mitotic dividing cells. Microtubule motor required for spindle body separation. Slow plus-end directed microtubule motor capable of cross-linking and sliding apart antiparallel microtubules, thereby pushing apart the associated spindle poles during spindle assembly and function. Forms cross-links between microtubules within interpolar microtubule bundles. Contributes to the length of the metaphase spindle, maintains the prometaphase spindle by antagonizing Ncd, drives anaphase B, and also contributes to normal chromosome congression, kinet [...] | Structural maintenance of chromosomes 2 (SMC2) encodes a condensin subunit involved in chromosome condensation and cell division. It contributes to neurogenesis and stem cell differentiation. | 0.959 |
Klp61F | asp | FBpp0072616 | FBpp0084071 | Kinesin-like protein Klp61F; Important role in mitotic dividing cells. Microtubule motor required for spindle body separation. Slow plus-end directed microtubule motor capable of cross-linking and sliding apart antiparallel microtubules, thereby pushing apart the associated spindle poles during spindle assembly and function. Forms cross-links between microtubules within interpolar microtubule bundles. Contributes to the length of the metaphase spindle, maintains the prometaphase spindle by antagonizing Ncd, drives anaphase B, and also contributes to normal chromosome congression, kinet [...] | Protein abnormal spindle; Required to maintain the structure of the centrosomal microtubule organizing center (MTOC) during mitosis. May have a preferential role in regulating neurogenesis. Required for germ cell mitosis and oocyte differentiation. | 0.971 |
Klp61F | aurB | FBpp0072616 | FBpp0079769 | Kinesin-like protein Klp61F; Important role in mitotic dividing cells. Microtubule motor required for spindle body separation. Slow plus-end directed microtubule motor capable of cross-linking and sliding apart antiparallel microtubules, thereby pushing apart the associated spindle poles during spindle assembly and function. Forms cross-links between microtubules within interpolar microtubule bundles. Contributes to the length of the metaphase spindle, maintains the prometaphase spindle by antagonizing Ncd, drives anaphase B, and also contributes to normal chromosome congression, kinet [...] | Aurora B (aurB) encodes a serine-threonine kinase and member of the chromosomal passenger complex. It plays multiple roles in mitosis including the correction of erroneous chromosome-spindle interactions, chromosome condensation, kinetochore assembly, spindle assembly checkpoint and cytokinesis. | 0.958 |
Klp61F | cmet | FBpp0072616 | FBpp0304511 | Kinesin-like protein Klp61F; Important role in mitotic dividing cells. Microtubule motor required for spindle body separation. Slow plus-end directed microtubule motor capable of cross-linking and sliding apart antiparallel microtubules, thereby pushing apart the associated spindle poles during spindle assembly and function. Forms cross-links between microtubules within interpolar microtubule bundles. Contributes to the length of the metaphase spindle, maintains the prometaphase spindle by antagonizing Ncd, drives anaphase B, and also contributes to normal chromosome congression, kinet [...] | CENP-meta, isoform C; CENP-meta (cmet) encodes a kinetochore kinesin that contributes to metaphase chromosome alignment; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.938 |
Klp61F | mars | FBpp0072616 | FBpp0311207 | Kinesin-like protein Klp61F; Important role in mitotic dividing cells. Microtubule motor required for spindle body separation. Slow plus-end directed microtubule motor capable of cross-linking and sliding apart antiparallel microtubules, thereby pushing apart the associated spindle poles during spindle assembly and function. Forms cross-links between microtubules within interpolar microtubule bundles. Contributes to the length of the metaphase spindle, maintains the prometaphase spindle by antagonizing Ncd, drives anaphase B, and also contributes to normal chromosome congression, kinet [...] | Mars (mars) encodes a microtubule-associated protein that shuttles between the mitotic spindle and the nucleus. It is required for mitotic spindle attachment to the centrosome; Belongs to the SAPAP family. | 0.950 |
Klp61F | ncd | FBpp0072616 | FBpp0311231 | Kinesin-like protein Klp61F; Important role in mitotic dividing cells. Microtubule motor required for spindle body separation. Slow plus-end directed microtubule motor capable of cross-linking and sliding apart antiparallel microtubules, thereby pushing apart the associated spindle poles during spindle assembly and function. Forms cross-links between microtubules within interpolar microtubule bundles. Contributes to the length of the metaphase spindle, maintains the prometaphase spindle by antagonizing Ncd, drives anaphase B, and also contributes to normal chromosome congression, kinet [...] | Protein claret segregational; Non-claret disjunctional (ncd) encodes a minus-end-directed kinesin microtubule motor protein and the sole member of the kinesin-14 motor family. It is required for spindle assembly in oocytes and chromosome attachment to spindles in early embryos; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. NCD subfamily. | 0.992 |
Klp61F | pav | FBpp0072616 | FBpp0073083 | Kinesin-like protein Klp61F; Important role in mitotic dividing cells. Microtubule motor required for spindle body separation. Slow plus-end directed microtubule motor capable of cross-linking and sliding apart antiparallel microtubules, thereby pushing apart the associated spindle poles during spindle assembly and function. Forms cross-links between microtubules within interpolar microtubule bundles. Contributes to the length of the metaphase spindle, maintains the prometaphase spindle by antagonizing Ncd, drives anaphase B, and also contributes to normal chromosome congression, kinet [...] | Kinesin-like protein; Pavarotti (pav) encodes a microtubule motor protein from the Kinesin superfamily. It plays important roles during the mitotic cycle including spindle formation, cortical cytoskeleton reorganization and cytokinesis. It also negatively regulates Wnt activity. | 0.985 |
Klp61F | scra | FBpp0072616 | FBpp0087986 | Kinesin-like protein Klp61F; Important role in mitotic dividing cells. Microtubule motor required for spindle body separation. Slow plus-end directed microtubule motor capable of cross-linking and sliding apart antiparallel microtubules, thereby pushing apart the associated spindle poles during spindle assembly and function. Forms cross-links between microtubules within interpolar microtubule bundles. Contributes to the length of the metaphase spindle, maintains the prometaphase spindle by antagonizing Ncd, drives anaphase B, and also contributes to normal chromosome congression, kinet [...] | Anillin; Required for cytokinesis. Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression and proper formation of the midbody. Required during cellularization of syncytial embryos for the proper formation and function of the furrow canals, the stable inward folds of the plasma membrane which separate the peripheral nuclei. Also required for the formation of the pole cells, the progenitors of the adult germline which are formed by cytokinesis of the cytoplasmic buds at the posterior pole of the syncytial embryo. Essential for embry [...] | 0.937 |
Klp61F | tum | FBpp0072616 | FBpp0086767 | Kinesin-like protein Klp61F; Important role in mitotic dividing cells. Microtubule motor required for spindle body separation. Slow plus-end directed microtubule motor capable of cross-linking and sliding apart antiparallel microtubules, thereby pushing apart the associated spindle poles during spindle assembly and function. Forms cross-links between microtubules within interpolar microtubule bundles. Contributes to the length of the metaphase spindle, maintains the prometaphase spindle by antagonizing Ncd, drives anaphase B, and also contributes to normal chromosome congression, kinet [...] | Tumbleweed (tum) encodes a GTPase activating protein for Rho family GTPases involved in Wnt signalling regulation. | 0.952 |
Klp67A | Klp61F | FBpp0312148 | FBpp0072616 | Kinesin-like protein at 67A (Klp67A) encodes a microtubule motor protein involved in chromosome congression and mitotic spindle morphogenesis; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Kinesin-like protein Klp61F; Important role in mitotic dividing cells. Microtubule motor required for spindle body separation. Slow plus-end directed microtubule motor capable of cross-linking and sliding apart antiparallel microtubules, thereby pushing apart the associated spindle poles during spindle assembly and function. Forms cross-links between microtubules within interpolar microtubule bundles. Contributes to the length of the metaphase spindle, maintains the prometaphase spindle by antagonizing Ncd, drives anaphase B, and also contributes to normal chromosome congression, kinet [...] | 0.994 |
Klp67A | SMC2 | FBpp0312148 | FBpp0086591 | Kinesin-like protein at 67A (Klp67A) encodes a microtubule motor protein involved in chromosome congression and mitotic spindle morphogenesis; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Structural maintenance of chromosomes 2 (SMC2) encodes a condensin subunit involved in chromosome condensation and cell division. It contributes to neurogenesis and stem cell differentiation. | 0.683 |
Klp67A | asp | FBpp0312148 | FBpp0084071 | Kinesin-like protein at 67A (Klp67A) encodes a microtubule motor protein involved in chromosome congression and mitotic spindle morphogenesis; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Protein abnormal spindle; Required to maintain the structure of the centrosomal microtubule organizing center (MTOC) during mitosis. May have a preferential role in regulating neurogenesis. Required for germ cell mitosis and oocyte differentiation. | 0.802 |
Klp67A | aurB | FBpp0312148 | FBpp0079769 | Kinesin-like protein at 67A (Klp67A) encodes a microtubule motor protein involved in chromosome congression and mitotic spindle morphogenesis; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Aurora B (aurB) encodes a serine-threonine kinase and member of the chromosomal passenger complex. It plays multiple roles in mitosis including the correction of erroneous chromosome-spindle interactions, chromosome condensation, kinetochore assembly, spindle assembly checkpoint and cytokinesis. | 0.873 |
Klp67A | cmet | FBpp0312148 | FBpp0304511 | Kinesin-like protein at 67A (Klp67A) encodes a microtubule motor protein involved in chromosome congression and mitotic spindle morphogenesis; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | CENP-meta, isoform C; CENP-meta (cmet) encodes a kinetochore kinesin that contributes to metaphase chromosome alignment; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | 0.917 |
Klp67A | mars | FBpp0312148 | FBpp0311207 | Kinesin-like protein at 67A (Klp67A) encodes a microtubule motor protein involved in chromosome congression and mitotic spindle morphogenesis; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Mars (mars) encodes a microtubule-associated protein that shuttles between the mitotic spindle and the nucleus. It is required for mitotic spindle attachment to the centrosome; Belongs to the SAPAP family. | 0.844 |
Klp67A | ncd | FBpp0312148 | FBpp0311231 | Kinesin-like protein at 67A (Klp67A) encodes a microtubule motor protein involved in chromosome congression and mitotic spindle morphogenesis; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Protein claret segregational; Non-claret disjunctional (ncd) encodes a minus-end-directed kinesin microtubule motor protein and the sole member of the kinesin-14 motor family. It is required for spindle assembly in oocytes and chromosome attachment to spindles in early embryos; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. NCD subfamily. | 0.896 |
Klp67A | pav | FBpp0312148 | FBpp0073083 | Kinesin-like protein at 67A (Klp67A) encodes a microtubule motor protein involved in chromosome congression and mitotic spindle morphogenesis; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Kinesin-like protein; Pavarotti (pav) encodes a microtubule motor protein from the Kinesin superfamily. It plays important roles during the mitotic cycle including spindle formation, cortical cytoskeleton reorganization and cytokinesis. It also negatively regulates Wnt activity. | 0.933 |
Klp67A | scra | FBpp0312148 | FBpp0087986 | Kinesin-like protein at 67A (Klp67A) encodes a microtubule motor protein involved in chromosome congression and mitotic spindle morphogenesis; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Anillin; Required for cytokinesis. Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression and proper formation of the midbody. Required during cellularization of syncytial embryos for the proper formation and function of the furrow canals, the stable inward folds of the plasma membrane which separate the peripheral nuclei. Also required for the formation of the pole cells, the progenitors of the adult germline which are formed by cytokinesis of the cytoplasmic buds at the posterior pole of the syncytial embryo. Essential for embry [...] | 0.730 |
Klp67A | tum | FBpp0312148 | FBpp0086767 | Kinesin-like protein at 67A (Klp67A) encodes a microtubule motor protein involved in chromosome congression and mitotic spindle morphogenesis; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. | Tumbleweed (tum) encodes a GTPase activating protein for Rho family GTPases involved in Wnt signalling regulation. | 0.705 |