STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIG-BGPI mannosyltransferase 3; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2- GlcN-acyl-PI during GPI precursor assembly (By similarity). Belongs to the glycosyltransferase 22 family. PIGB subfamily. (561 aa)    
Predicted Functional Partners:
PIG-M
GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly.
   
 
 0.996
PIG-V
GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly. Required for the GPI-mediated endoplasmic reticulum exit and proper targeting to the cell surface of chp. Required for GPI-mediated membrane attachment of chp, qsm and Cont. Essential for microvillar stability in the rhabdomere; Belongs to the PIGV family.
    
 0.996
PIG-O
Phosphatidylinositol glycan anchor biosynthesis class O; Mannose-ethanolamine phosphotransferase activity. It is involved in the biological process described with: GPI anchor biosynthetic process.
   
 
 0.994
PIG-N
Phosphatidylinositol glycan anchor biosynthesis class N; Mannose-ethanolamine phosphotransferase activity. It is involved in the biological process described with: GPI anchor biosynthetic process.
     
 0.987
PIG-F
Phosphatidylinositol glycan anchor biosynthesis class F; Mannose-ethanolamine phosphotransferase activity. It is involved in the biological process described with: GPI anchor biosynthetic process.
     
 0.984
PIG-X
Phosphatidylinositol glycan anchor biosynthesis class X, isoform C; It is involved in the biological process described with: GPI anchor biosynthetic process.
     
 0.960
PIG-A
Phosphatidylinositol glycan anchor biosynthesis class A, isoform A; Phosphatidylinositol N-acetylglucosaminyltransferase activity. It is involved in the biological process described with: GPI anchor biosynthetic process.
   
  
 0.939
PIG-C
Phosphatidylinositol glycan anchor biosynthesis class C (PIG-C) encodes a subunit of GPI-GlcNAc transferase, which catalyzes the first reaction in the biosynthesis of the glycosylphosphatidylinositol (GPI)-anchor.
   
  
 0.939
PIG-P
Phosphatidylinositol glycan anchor biosynthesis class P; Phosphatidylinositol N-acetylglucosaminyltransferase activity. It is involved in the biological process described with: GPI anchor biosynthetic process.
   
 
 0.936
PIG-G
Phosphatidylinositol glycan anchor biosynthesis class G; CP2 mannose-ethanolamine phosphotransferase activity. It is involved in the biological process described with: GPI anchor biosynthetic process.
   
 
 0.936
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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