STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG7514AT25476p; Oxoglutarate:malate antiporter activity. It is involved in the biological process described with: mitochondrial transport; alpha-ketoglutarate transport; malate transport; Belongs to the mitochondrial carrier (TC 2.A.29) family. (301 aa)    
Predicted Functional Partners:
ND-49L
NADH dehydrogenase activity; quinone binding; NADH dehydrogenase (ubiquinone) activity; NAD binding. It is involved in the biological process described with: mitochondrial electron transport, NADH to ubiquinone; Belongs to the complex I 49 kDa subunit family.
   
  
 0.902
SdhAL
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
   
 
 0.805
Cyt-c1L
Cytochrome c1-like; Heme binding; electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity. It is involved in the biological process described with: mitochondrial electron transport, ubiquinol to cytochrome c; mitochondrial ATP synthesis coupled proton transport.
   
 
 0.771
UQCR-14L
Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family.
   
 
 0.756
CG10749
L-malate dehydrogenase activity. It is involved in the biological process described with: carbohydrate metabolic process; malate metabolic process; tricarboxylic acid cycle.
   
  
 0.716
CG9920
AT30951p; Chaperone binding; unfolded protein binding; metal ion binding. It is involved in the biological process described with: chaperone cofactor-dependent protein refolding; Belongs to the GroES chaperonin family.
   
  
 0.716
tomboy40
Mitochondrial import receptor subunit TOM40 homolog 2; Channel-forming protein essential for import of protein precursors into mitochondria; Belongs to the Tom40 family.
   
 
 0.712
CG14137
Uncharacterized protein.
      
 0.678
CG12910
Glycosyltransferase family 92 protein; UDP-galactosyltransferase activity. It is involved in the biological process described with: N-glycan processing; Belongs to the glycosyltransferase 92 family.
      
 0.671
D19A
RE29310p; DNA binding; zinc ion binding; DNA-binding transcription factor activity. It is involved in the biological process described with: regulation of transcription, DNA-templated.
      
 0.669
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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