Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CG12782 | Nup153 | FBpp0071957 | FBpp0309144 | WD_REPEATS_REGION domain-containing protein; Ubiquitin binding; RNA binding. It is involved in the biological process described with: RNA export from nucleus; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery; mRNA export from nucleus. | Nuclear pore complex protein Nup153; Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC. Essential for the nuclear import of nuclear localization signal (NLS)-containing proteins in a Importin alpha/Importin beta receptor-dependent manner. Required for nuclear import of Mad. Plays a role in chromosomal organization and gene expression regulation; stimulates transcription by promoting the formation of an open chromatin environment. Binds chromatin to nucleopor [...] | 0.765 |
| CG12782 | Nup214 | FBpp0071957 | FBpp0071905 | WD_REPEATS_REGION domain-containing protein; Ubiquitin binding; RNA binding. It is involved in the biological process described with: RNA export from nucleus; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery; mRNA export from nucleus. | Nuclear pore complex protein Nup214; Serves as a docking site in the receptor-mediated import of substrates across the nuclear pore complex including emb, RanGAP and phosphorylated Mad. Protects mbo/Nup88 from proteasomal degradation at the nuclear pore. Together with mbo/Nup88, sequesters emb in the cytoplasm and thereby attenuates nuclear export signal (NES)-mediated nuclear export. Together with mbo/Nup88, required for the nuclear import of the Rel family transcription factors dorsal (dl) and Dorsal-related immunity factor (Dif) and the activation of an immune response. | 0.937 |
| CG12782 | Nup62 | FBpp0071957 | FBpp0086294 | WD_REPEATS_REGION domain-containing protein; Ubiquitin binding; RNA binding. It is involved in the biological process described with: RNA export from nucleus; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery; mRNA export from nucleus. | Nuclear pore glycoprotein p62; Essential component of the nuclear pore complex (By similarity). The N-terminal is probably involved in nucleocytoplasmic transport (By similarity). The C-terminal is involved in protein- protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of Nup62 to the pore complex (By similarity). Binds to transcriptionally active genes. Negatively regulates chromatin attachment to the nuclear envelope, probably by preventing chromatin tethering by Nup154. | 0.719 |
| CG12782 | Nxt1 | FBpp0071957 | FBpp0072150 | WD_REPEATS_REGION domain-containing protein; Ubiquitin binding; RNA binding. It is involved in the biological process described with: RNA export from nucleus; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery; mRNA export from nucleus. | NTF2-related export protein; Stimulator of protein export for NES-containing proteins (By similarity). Plays a role in the nuclear export of mRNA. Also plays a role in the nuclear export of U1 snRNA, tRNA, and mRNA (By similarity). In the ovaries, forms a complex with nxf2, Panx and piwi which acts as effectors of cotranscriptional transposon silencing. | 0.773 |
| CG12782 | Rae1 | FBpp0071957 | FBpp0071600 | WD_REPEATS_REGION domain-containing protein; Ubiquitin binding; RNA binding. It is involved in the biological process described with: RNA export from nucleus; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery; mRNA export from nucleus. | Rae1 (Rae1) encodes a nucleoporin member of the WD40-repeat beta propeller protein super family. Biological roles of the pleiotropic Rae1 gene product include poly(A)+ mRNA export, cell cycle regulation, male meiosis control and male germ cell post-meiotic differentiation. | 0.939 |
| CG12782 | Ref1 | FBpp0071957 | FBpp0081156 | WD_REPEATS_REGION domain-containing protein; Ubiquitin binding; RNA binding. It is involved in the biological process described with: RNA export from nucleus; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery; mRNA export from nucleus. | RNA and export factor binding protein 1; mRNA binding; nucleic acid binding. It is involved in the biological process described with: mRNA splicing, via spliceosome. | 0.780 |
| CG12782 | Ref2 | FBpp0071957 | FBpp0300958 | WD_REPEATS_REGION domain-containing protein; Ubiquitin binding; RNA binding. It is involved in the biological process described with: RNA export from nucleus; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery; mRNA export from nucleus. | RNA and export factor binding protein 2, isoform A; mRNA binding; nucleic acid binding. | 0.667 |
| CG12782 | sbr | FBpp0071957 | FBpp0073267 | WD_REPEATS_REGION domain-containing protein; Ubiquitin binding; RNA binding. It is involved in the biological process described with: RNA export from nucleus; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery; mRNA export from nucleus. | Nuclear RNA export factor 1; Mediates the export of the majority of mRNAs from the nucleus to the cytoplasm. | 0.994 |
| CG12782 | thoc5 | FBpp0071957 | FBpp0072056 | WD_REPEATS_REGION domain-containing protein; Ubiquitin binding; RNA binding. It is involved in the biological process described with: RNA export from nucleus; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery; mRNA export from nucleus. | THO complex subunit 5; The THO complex is required for cell proliferation and for proper export of heat-shock mRNAs under heat stress. Belongs to the THOC5 family. | 0.768 |
| Nup153 | CG12782 | FBpp0309144 | FBpp0071957 | Nuclear pore complex protein Nup153; Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC. Essential for the nuclear import of nuclear localization signal (NLS)-containing proteins in a Importin alpha/Importin beta receptor-dependent manner. Required for nuclear import of Mad. Plays a role in chromosomal organization and gene expression regulation; stimulates transcription by promoting the formation of an open chromatin environment. Binds chromatin to nucleopor [...] | WD_REPEATS_REGION domain-containing protein; Ubiquitin binding; RNA binding. It is involved in the biological process described with: RNA export from nucleus; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery; mRNA export from nucleus. | 0.765 |
| Nup153 | Nup214 | FBpp0309144 | FBpp0071905 | Nuclear pore complex protein Nup153; Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC. Essential for the nuclear import of nuclear localization signal (NLS)-containing proteins in a Importin alpha/Importin beta receptor-dependent manner. Required for nuclear import of Mad. Plays a role in chromosomal organization and gene expression regulation; stimulates transcription by promoting the formation of an open chromatin environment. Binds chromatin to nucleopor [...] | Nuclear pore complex protein Nup214; Serves as a docking site in the receptor-mediated import of substrates across the nuclear pore complex including emb, RanGAP and phosphorylated Mad. Protects mbo/Nup88 from proteasomal degradation at the nuclear pore. Together with mbo/Nup88, sequesters emb in the cytoplasm and thereby attenuates nuclear export signal (NES)-mediated nuclear export. Together with mbo/Nup88, required for the nuclear import of the Rel family transcription factors dorsal (dl) and Dorsal-related immunity factor (Dif) and the activation of an immune response. | 0.999 |
| Nup153 | Nup62 | FBpp0309144 | FBpp0086294 | Nuclear pore complex protein Nup153; Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC. Essential for the nuclear import of nuclear localization signal (NLS)-containing proteins in a Importin alpha/Importin beta receptor-dependent manner. Required for nuclear import of Mad. Plays a role in chromosomal organization and gene expression regulation; stimulates transcription by promoting the formation of an open chromatin environment. Binds chromatin to nucleopor [...] | Nuclear pore glycoprotein p62; Essential component of the nuclear pore complex (By similarity). The N-terminal is probably involved in nucleocytoplasmic transport (By similarity). The C-terminal is involved in protein- protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of Nup62 to the pore complex (By similarity). Binds to transcriptionally active genes. Negatively regulates chromatin attachment to the nuclear envelope, probably by preventing chromatin tethering by Nup154. | 0.995 |
| Nup153 | Nxt1 | FBpp0309144 | FBpp0072150 | Nuclear pore complex protein Nup153; Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC. Essential for the nuclear import of nuclear localization signal (NLS)-containing proteins in a Importin alpha/Importin beta receptor-dependent manner. Required for nuclear import of Mad. Plays a role in chromosomal organization and gene expression regulation; stimulates transcription by promoting the formation of an open chromatin environment. Binds chromatin to nucleopor [...] | NTF2-related export protein; Stimulator of protein export for NES-containing proteins (By similarity). Plays a role in the nuclear export of mRNA. Also plays a role in the nuclear export of U1 snRNA, tRNA, and mRNA (By similarity). In the ovaries, forms a complex with nxf2, Panx and piwi which acts as effectors of cotranscriptional transposon silencing. | 0.701 |
| Nup153 | Rae1 | FBpp0309144 | FBpp0071600 | Nuclear pore complex protein Nup153; Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC. Essential for the nuclear import of nuclear localization signal (NLS)-containing proteins in a Importin alpha/Importin beta receptor-dependent manner. Required for nuclear import of Mad. Plays a role in chromosomal organization and gene expression regulation; stimulates transcription by promoting the formation of an open chromatin environment. Binds chromatin to nucleopor [...] | Rae1 (Rae1) encodes a nucleoporin member of the WD40-repeat beta propeller protein super family. Biological roles of the pleiotropic Rae1 gene product include poly(A)+ mRNA export, cell cycle regulation, male meiosis control and male germ cell post-meiotic differentiation. | 0.966 |
| Nup153 | Ref1 | FBpp0309144 | FBpp0081156 | Nuclear pore complex protein Nup153; Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC. Essential for the nuclear import of nuclear localization signal (NLS)-containing proteins in a Importin alpha/Importin beta receptor-dependent manner. Required for nuclear import of Mad. Plays a role in chromosomal organization and gene expression regulation; stimulates transcription by promoting the formation of an open chromatin environment. Binds chromatin to nucleopor [...] | RNA and export factor binding protein 1; mRNA binding; nucleic acid binding. It is involved in the biological process described with: mRNA splicing, via spliceosome. | 0.714 |
| Nup153 | Upf3 | FBpp0309144 | FBpp0072130 | Nuclear pore complex protein Nup153; Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC. Essential for the nuclear import of nuclear localization signal (NLS)-containing proteins in a Importin alpha/Importin beta receptor-dependent manner. Required for nuclear import of Mad. Plays a role in chromosomal organization and gene expression regulation; stimulates transcription by promoting the formation of an open chromatin environment. Binds chromatin to nucleopor [...] | Upf3, isoform B; Upf3 (Upf3) encodes a protein that regulates targets of the nonsense-mediated mRNA decay pathway. This pathway participates in homeostatic gene expression regulation and plays a quality control role in the elimination of mRNAs with premature termination codons. The product of Upf3 is involved in cell cycle progression and general developmental rate. | 0.501 |
| Nup153 | sbr | FBpp0309144 | FBpp0073267 | Nuclear pore complex protein Nup153; Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC. Essential for the nuclear import of nuclear localization signal (NLS)-containing proteins in a Importin alpha/Importin beta receptor-dependent manner. Required for nuclear import of Mad. Plays a role in chromosomal organization and gene expression regulation; stimulates transcription by promoting the formation of an open chromatin environment. Binds chromatin to nucleopor [...] | Nuclear RNA export factor 1; Mediates the export of the majority of mRNAs from the nucleus to the cytoplasm. | 0.948 |
| Nup214 | CG12782 | FBpp0071905 | FBpp0071957 | Nuclear pore complex protein Nup214; Serves as a docking site in the receptor-mediated import of substrates across the nuclear pore complex including emb, RanGAP and phosphorylated Mad. Protects mbo/Nup88 from proteasomal degradation at the nuclear pore. Together with mbo/Nup88, sequesters emb in the cytoplasm and thereby attenuates nuclear export signal (NES)-mediated nuclear export. Together with mbo/Nup88, required for the nuclear import of the Rel family transcription factors dorsal (dl) and Dorsal-related immunity factor (Dif) and the activation of an immune response. | WD_REPEATS_REGION domain-containing protein; Ubiquitin binding; RNA binding. It is involved in the biological process described with: RNA export from nucleus; transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery; mRNA export from nucleus. | 0.937 |
| Nup214 | Nup153 | FBpp0071905 | FBpp0309144 | Nuclear pore complex protein Nup214; Serves as a docking site in the receptor-mediated import of substrates across the nuclear pore complex including emb, RanGAP and phosphorylated Mad. Protects mbo/Nup88 from proteasomal degradation at the nuclear pore. Together with mbo/Nup88, sequesters emb in the cytoplasm and thereby attenuates nuclear export signal (NES)-mediated nuclear export. Together with mbo/Nup88, required for the nuclear import of the Rel family transcription factors dorsal (dl) and Dorsal-related immunity factor (Dif) and the activation of an immune response. | Nuclear pore complex protein Nup153; Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC. Essential for the nuclear import of nuclear localization signal (NLS)-containing proteins in a Importin alpha/Importin beta receptor-dependent manner. Required for nuclear import of Mad. Plays a role in chromosomal organization and gene expression regulation; stimulates transcription by promoting the formation of an open chromatin environment. Binds chromatin to nucleopor [...] | 0.999 |
| Nup214 | Nup62 | FBpp0071905 | FBpp0086294 | Nuclear pore complex protein Nup214; Serves as a docking site in the receptor-mediated import of substrates across the nuclear pore complex including emb, RanGAP and phosphorylated Mad. Protects mbo/Nup88 from proteasomal degradation at the nuclear pore. Together with mbo/Nup88, sequesters emb in the cytoplasm and thereby attenuates nuclear export signal (NES)-mediated nuclear export. Together with mbo/Nup88, required for the nuclear import of the Rel family transcription factors dorsal (dl) and Dorsal-related immunity factor (Dif) and the activation of an immune response. | Nuclear pore glycoprotein p62; Essential component of the nuclear pore complex (By similarity). The N-terminal is probably involved in nucleocytoplasmic transport (By similarity). The C-terminal is involved in protein- protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of Nup62 to the pore complex (By similarity). Binds to transcriptionally active genes. Negatively regulates chromatin attachment to the nuclear envelope, probably by preventing chromatin tethering by Nup154. | 0.999 |
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