| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CG30496 | CG32650 | FBpp0088000 | FBpp0073531 | RE73310p; Ubiquitin-protein transferase inhibitor activity; ubiquitin protein ligase binding. It is involved in the biological process described with: negative regulation of protein ubiquitination. | Uncharacterized protein. | 0.467 |
| CG30496 | CG9410 | FBpp0088000 | FBpp0085450 | RE73310p; Ubiquitin-protein transferase inhibitor activity; ubiquitin protein ligase binding. It is involved in the biological process described with: negative regulation of protein ubiquitination. | Coenzyme Q-binding protein COQ10, mitochondrial; Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes (By similarity); Belongs to the COQ10 family. | 0.627 |
| CG30496 | Coq2 | FBpp0088000 | FBpp0081347 | RE73310p; Ubiquitin-protein transferase inhibitor activity; ubiquitin protein ligase binding. It is involved in the biological process described with: negative regulation of protein ubiquitination. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate; Belongs to the UbiA prenyltransferase family. | 0.650 |
| CG30496 | Coq3 | FBpp0088000 | FBpp0081028 | RE73310p; Ubiquitin-protein transferase inhibitor activity; ubiquitin protein ligase binding. It is involved in the biological process described with: negative regulation of protein ubiquitination. | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | 0.776 |
| CG30496 | Coq4 | FBpp0088000 | FBpp0289097 | RE73310p; Ubiquitin-protein transferase inhibitor activity; ubiquitin protein ligase binding. It is involved in the biological process described with: negative regulation of protein ubiquitination. | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides. | 0.802 |
| CG30496 | Coq5 | FBpp0088000 | FBpp0311954 | RE73310p; Ubiquitin-protein transferase inhibitor activity; ubiquitin protein ligase binding. It is involved in the biological process described with: negative regulation of protein ubiquitination. | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | 0.780 |
| CG30496 | Coq6 | FBpp0088000 | FBpp0078759 | RE73310p; Ubiquitin-protein transferase inhibitor activity; ubiquitin protein ligase binding. It is involved in the biological process described with: negative regulation of protein ubiquitination. | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | 0.820 |
| CG30496 | Coq7 | FBpp0088000 | FBpp0070924 | RE73310p; Ubiquitin-protein transferase inhibitor activity; ubiquitin protein ligase binding. It is involved in the biological process described with: negative regulation of protein ubiquitination. | 5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. | 0.948 |
| CG30496 | Coq8 | FBpp0088000 | FBpp0073530 | RE73310p; Ubiquitin-protein transferase inhibitor activity; ubiquitin protein ligase binding. It is involved in the biological process described with: negative regulation of protein ubiquitination. | Coenzyme Q8; Protein kinase activity; kinase activity. It is involved in the biological process described with: mitochondrial electron transport, ubiquinol to cytochrome c; ubiquinone biosynthetic process. | 0.852 |
| CG30496 | Pdss2 | FBpp0088000 | FBpp0077945 | RE73310p; Ubiquitin-protein transferase inhibitor activity; ubiquitin protein ligase binding. It is involved in the biological process described with: negative regulation of protein ubiquitination. | Decaprenyl diphosphate synthase subunit 2, isoform A; Prenyltransferase activity; trans-hexaprenyltranstransferase activity. It is involved in the biological process described with: isoprenoid biosynthetic process; ubiquinone biosynthetic process; Belongs to the FPP/GGPP synthase family. | 0.608 |
| CG32650 | CG30496 | FBpp0073531 | FBpp0088000 | Uncharacterized protein. | RE73310p; Ubiquitin-protein transferase inhibitor activity; ubiquitin protein ligase binding. It is involved in the biological process described with: negative regulation of protein ubiquitination. | 0.467 |
| CG32650 | Coq3 | FBpp0073531 | FBpp0081028 | Uncharacterized protein. | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | 0.443 |
| CG32650 | Coq5 | FBpp0073531 | FBpp0311954 | Uncharacterized protein. | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | 0.522 |
| CG32650 | Coq7 | FBpp0073531 | FBpp0070924 | Uncharacterized protein. | 5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. | 0.431 |
| CG32650 | Coq8 | FBpp0073531 | FBpp0073530 | Uncharacterized protein. | Coenzyme Q8; Protein kinase activity; kinase activity. It is involved in the biological process described with: mitochondrial electron transport, ubiquinol to cytochrome c; ubiquinone biosynthetic process. | 0.793 |
| CG9410 | CG30496 | FBpp0085450 | FBpp0088000 | Coenzyme Q-binding protein COQ10, mitochondrial; Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes (By similarity); Belongs to the COQ10 family. | RE73310p; Ubiquitin-protein transferase inhibitor activity; ubiquitin protein ligase binding. It is involved in the biological process described with: negative regulation of protein ubiquitination. | 0.627 |
| CG9410 | Coq2 | FBpp0085450 | FBpp0081347 | Coenzyme Q-binding protein COQ10, mitochondrial; Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes (By similarity); Belongs to the COQ10 family. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate; Belongs to the UbiA prenyltransferase family. | 0.655 |
| CG9410 | Coq3 | FBpp0085450 | FBpp0081028 | Coenzyme Q-binding protein COQ10, mitochondrial; Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes (By similarity); Belongs to the COQ10 family. | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | 0.602 |
| CG9410 | Coq4 | FBpp0085450 | FBpp0289097 | Coenzyme Q-binding protein COQ10, mitochondrial; Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes (By similarity); Belongs to the COQ10 family. | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides. | 0.624 |
| CG9410 | Coq5 | FBpp0085450 | FBpp0311954 | Coenzyme Q-binding protein COQ10, mitochondrial; Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes (By similarity); Belongs to the COQ10 family. | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | 0.457 |