STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG1622FI05227p; It is involved in the biological process described with: mRNA splicing, via spliceosome. (398 aa)    
Predicted Functional Partners:
Prp38
Pre-mRNA-splicing factor 38; Required for pre-mRNA splicing; Belongs to the PRP38 family.
   
 
 
0.904
Uch-L5R
Ubiquitin carboxyl-terminal hydrolase; Thiol-dependent ubiquitin-specific protease activity. It is involved in the biological process described with: protein deubiquitination; ubiquitin-dependent protein catabolic process.
 
      0.845
Pnn
Pinin, isoform B; It is involved in the biological process described with: mRNA splicing, via spliceosome; cell adhesion.
   
    0.793
CG4119
BcDNA.LD23634; mRNA binding. It is involved in the biological process described with: regulation of alternative mRNA splicing, via spliceosome; mRNA splicing, via spliceosome.
   
  
 0.791
Srp54
LD29830p; Srp54 (Srp54) encodes a protein that regulates mRNA alternative splicing, the processing of the mRNA 3'-end and the selection of the transcriptional start site.
   
 
 0.719
CG3198
RH42690p; mRNA binding. It is involved in the biological process described with: mRNA splice site selection; mRNA splicing, via spliceosome; positive regulation of gene expression.
   
 
 0.710
Prp4k
Uncharacterized protein, isoform C; Protein serine/threonine kinase activity; protein kinase activity; ATP binding. It is involved in the biological process described with: protein phosphorylation; mRNA splicing, via spliceosome; positive regulation of hippo signaling.
   
    0.641
Ubi-p63E
Polyubiquitin; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degradatio [...]
    
   0.606
CG11700
Ubiquitin protein ligase binding; protein tag. It is involved in the biological process described with: determination of adult lifespan; negative regulation of reproductive process; modification-dependent protein catabolic process; protein ubiquitination.
    
   0.606
Ubi-p5E
Ubiquitin-5E, isoform A; Protein tag; ubiquitin protein ligase binding. It is involved in the biological process described with: ubiquitin-dependent protein catabolic process; protein ubiquitination; modification-dependent protein catabolic process; cellular protein modification process.
    
   0.606
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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