node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Akr1B | Eno | FBpp0075869 | FBpp0077572 | AT18092p; Indanol dehydrogenase activity; alcohol dehydrogenase (NADP+) activity; oxidoreductase activity; alditol:NADP+ 1-oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. | Enolase (Eno) encodes a phosphopyruvate hydratase involved in glucose homeostasis; Belongs to the enolase family. | 0.781 |
Akr1B | Gapdh2 | FBpp0075869 | FBpp0073922 | AT18092p; Indanol dehydrogenase activity; alcohol dehydrogenase (NADP+) activity; oxidoreductase activity; alditol:NADP+ 1-oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. | Glyceraldehyde 3 phosphate dehydrogenase 2 (Gapdh2) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glucose homeostasis; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.848 |
Akr1B | GstD1 | FBpp0075869 | FBpp0099824 | AT18092p; Indanol dehydrogenase activity; alcohol dehydrogenase (NADP+) activity; oxidoreductase activity; alditol:NADP+ 1-oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. | Glutathione S-transferase D1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has DDT dehydrochlorinase activity. May be involved in detoxification. | 0.778 |
Akr1B | Jafrac1 | FBpp0075869 | FBpp0308757 | AT18092p; Indanol dehydrogenase activity; alcohol dehydrogenase (NADP+) activity; oxidoreductase activity; alditol:NADP+ 1-oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. | Peroxiredoxin 1; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2) (By similarity). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron diffe [...] | 0.860 |
Akr1B | PHGPx | FBpp0075869 | FBpp0072932 | AT18092p; Indanol dehydrogenase activity; alcohol dehydrogenase (NADP+) activity; oxidoreductase activity; alditol:NADP+ 1-oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. | PHGPx (PHGPx) encodes a peroxidase involved in intestinal stem cell homeostasis and the response to endoplasmic reticulum stress. | 0.459 |
CG6762 | CG6888 | FBpp0074266 | FBpp0075397 | Putative sulfiredoxin; Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in a peroxiredoxin. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase (By similarity); Belongs to the sulfiredoxin family. | AT16346p; Thioredoxin peroxidase activity. | 0.849 |
CG6762 | Jafrac1 | FBpp0074266 | FBpp0308757 | Putative sulfiredoxin; Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in a peroxiredoxin. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase (By similarity); Belongs to the sulfiredoxin family. | Peroxiredoxin 1; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2) (By similarity). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron diffe [...] | 0.959 |
CG6762 | PHGPx | FBpp0074266 | FBpp0072932 | Putative sulfiredoxin; Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in a peroxiredoxin. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase (By similarity); Belongs to the sulfiredoxin family. | PHGPx (PHGPx) encodes a peroxidase involved in intestinal stem cell homeostasis and the response to endoplasmic reticulum stress. | 0.673 |
CG6762 | Prx5 | FBpp0074266 | FBpp0100079 | Putative sulfiredoxin; Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in a peroxiredoxin. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase (By similarity); Belongs to the sulfiredoxin family. | Peroxiredoxin 5 (Prx5) encodes an atypical member of the family of thiol-specific peroxidases that forms intramolecular disulfide bonds during the catalytic cycle. Its roles include antioxidant function, maintenance of cellular redox state, modulation of the immune-related signaling and protection against apoptosis. | 0.831 |
CG6762 | Trx-2 | FBpp0074266 | FBpp0079436 | Putative sulfiredoxin; Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in a peroxiredoxin. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase (By similarity); Belongs to the sulfiredoxin family. | Thioredoxin-2; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. As a reducing substrate of peroxiredoxin 1, thioredoxin 2 is preferred over thioredoxin 1. | 0.536 |
CG6888 | CG6762 | FBpp0075397 | FBpp0074266 | AT16346p; Thioredoxin peroxidase activity. | Putative sulfiredoxin; Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in a peroxiredoxin. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase (By similarity); Belongs to the sulfiredoxin family. | 0.849 |
CG6888 | Eno | FBpp0075397 | FBpp0077572 | AT16346p; Thioredoxin peroxidase activity. | Enolase (Eno) encodes a phosphopyruvate hydratase involved in glucose homeostasis; Belongs to the enolase family. | 0.551 |
CG6888 | Jafrac1 | FBpp0075397 | FBpp0308757 | AT16346p; Thioredoxin peroxidase activity. | Peroxiredoxin 1; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2) (By similarity). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron diffe [...] | 0.902 |
CG6888 | PHGPx | FBpp0075397 | FBpp0072932 | AT16346p; Thioredoxin peroxidase activity. | PHGPx (PHGPx) encodes a peroxidase involved in intestinal stem cell homeostasis and the response to endoplasmic reticulum stress. | 0.608 |
CG6888 | Prx5 | FBpp0075397 | FBpp0100079 | AT16346p; Thioredoxin peroxidase activity. | Peroxiredoxin 5 (Prx5) encodes an atypical member of the family of thiol-specific peroxidases that forms intramolecular disulfide bonds during the catalytic cycle. Its roles include antioxidant function, maintenance of cellular redox state, modulation of the immune-related signaling and protection against apoptosis. | 0.844 |
CG6888 | Trx-2 | FBpp0075397 | FBpp0079436 | AT16346p; Thioredoxin peroxidase activity. | Thioredoxin-2; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. As a reducing substrate of peroxiredoxin 1, thioredoxin 2 is preferred over thioredoxin 1. | 0.839 |
CG6888 | dhd | FBpp0075397 | FBpp0311766 | AT16346p; Thioredoxin peroxidase activity. | Thioredoxin-1; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. As a reducing substrate of peroxiredoxin 1, thioredoxin 2 is preferred over thioredoxin 1. Required for female meiosis and early embryonic development. | 0.665 |
Eno | Akr1B | FBpp0077572 | FBpp0075869 | Enolase (Eno) encodes a phosphopyruvate hydratase involved in glucose homeostasis; Belongs to the enolase family. | AT18092p; Indanol dehydrogenase activity; alcohol dehydrogenase (NADP+) activity; oxidoreductase activity; alditol:NADP+ 1-oxidoreductase activity. It is involved in the biological process described with: oxidation-reduction process. | 0.781 |
Eno | CG6888 | FBpp0077572 | FBpp0075397 | Enolase (Eno) encodes a phosphopyruvate hydratase involved in glucose homeostasis; Belongs to the enolase family. | AT16346p; Thioredoxin peroxidase activity. | 0.551 |
Eno | Gapdh2 | FBpp0077572 | FBpp0073922 | Enolase (Eno) encodes a phosphopyruvate hydratase involved in glucose homeostasis; Belongs to the enolase family. | Glyceraldehyde 3 phosphate dehydrogenase 2 (Gapdh2) encodes a glyceraldehyde-3-phosphate dehydrogenase involved in glucose homeostasis; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.995 |