STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG4301ATPase-coupled intramembrane lipid transporter activity; ATP binding; magnesium ion binding. It is involved in the biological process described with: phospholipid translocation; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1342 aa)    
Predicted Functional Partners:
CG33127
IP10114p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
   
  
 0.914
CDC50
CDC50, isoform A; It is involved in the biological process described with: phospholipid transport; Belongs to the CDC50/LEM3 family.
   
 
 0.885
Tsp42Ec
Tetraspanin.
   
  
 0.863
CG10353
Anoctamin; Chloride channel activity; protein dimerization activity; intracellular calcium activated chloride channel activity. It is involved in the biological process described with: transmembrane transport; chloride transmembrane transport; chloride transport.
   
  
 0.838
rtet
Tetracycline resistance; Transporter activity. It is involved in the biological process described with: transmembrane transport.
   
  
 0.836
CG15651
FI03527p; It is involved in the biological process described with: protein O-linked mannosylation.
   
   0.834
CG5096
RE59088p.
   
 
 0.818
CG10505
Uncharacterized protein; CG10505 encodes an ABC transporter whose expression is induced by excess copper, zinc, and cadmium. It is a target of the metal-responsive transcription factor encoded by MTF-1.
   
 
 0.813
Tsp42Er
Tetraspanin.
   
  
 0.797
fliI
Protein flightless-1; May play a key role in embryonic cellularization by interacting with both the cytoskeleton and other cellular components. Alternatively, it may play a structural role in indirect flight muscle. Vital for embryonic development; Belongs to the villin/gelsolin family.
   
   0.752
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.